Latest

neurodegeneration

Featured Genetics Neurology Neuroscience

·May 13, 2026·8 min read

APOE2 Protects Neurons from DNA Damage and Aging

Researchers discovered that the APOE2 gene variant shields the brain by helping neurons repair DNA damage and resist cellular senescence. By shifting focus from lipid transport to genomic integrity, this study identifies a new biological mechanism for longevity and suggests that mimicking APOE2's effects could lead to breakthrough treatments for Alzheimer’s disease.

Featured Neurology Neuroscience

·May 12, 2026·7 min read

Slowing Parkinson’s by Blocking a Key Protein

A new study found that GPNMB, released by the brain's immune cells, accelerates the spread of toxic alpha-synuclein. By using monoclonal antibodies to block GPNMB, the team successfully interrupted the cycle of neurodegeneration in preclinical models. This discovery provides a new therapeutic target that could finally slow the progression of Parkinson’s at its earliest stages.

Featured Neurology Neuroscience

·May 8, 2026·8 min read

Brain Pathway Identification Could Slow Parkinson’s

Researchers identified a sex-specific pathway that preserves dopamine-producing neurons in females. By reinforcing nicotine-responsive receptors without using nicotine, the team successfully reduced signs of degeneration, marking a critical step toward disease-modifying therapies.

Featured Neurology Neuroscience

·April 22, 2026·7 min read

White Matter Damage Triggers Repair and Disease Cycles

Researchers found that localized white matter damage causes remote grey matter loss, but regenerating myelin can reverse the damage.

Featured Neurology Neuroscience

·April 20, 2026·9 min read

Gut Bacteria May Predict Parkinson’s Before Symptoms Appear

A major study identifies 176 gut microbe species that signal Parkinson’s risk years before symptoms, suggesting that gut health is a key early warning system for the disease.

Featured Genetics Neuroscience

·April 18, 2026·8 min read

Glutathione Prevents Cellular Clogs

Researchers have identified SLC33A1 as the key transporter that maintains the ER’s glutathione balance, ensuring proteins fold correctly and preventing the "cellular debris" linked to neurodegeneration.

Featured Neuroscience

·April 7, 2026·8 min read

Cnpy1 Protects Stressed Neurons

Researchers have identified the Cnpy1 protein as a vital survival factor for pheromone-detecting neurons. The study shows how these specialized cells co-opt "ER-stress" pathways to function, with Cnpy1 acting as a cellular stabilizer.

Featured Neurology Neuroscience

·March 27, 2026·8 min read

AI Links Brain Rhythms to Physical “Wiring” Across Lifespan

A study of 1,965 people aged 5–100 reveals that brain wave speed is dictated by the brain's physical wiring. The new Xi–αNET model shows that slowing alpha waves are a direct marker of declining white matter in aging.

Featured Neurology Neuroscience Psychology

·March 24, 2026·9 min read

Depression and Gut Issues Linked to Future PSP

A new study identified five key risk factors for Progressive Supranuclear Palsy (PSP), including depression 10 years pre-diagnosis. The findings suggest the disease develops silently for a decade before motor symptoms appear.

This shows a brain and its cardiovascular network.

Featured Neurology Neuroscience

·March 21, 2026·7 min read

How Blood-Brain Barrier Failure Drives CTE in Athletes

A new study identifies a leaky blood-brain barrier as the "missing link" between repetitive head impacts and dementia in retired athletes. Researchers found that this persistent leakage triggers a toxic buildup of proteins, offering a new target for early diagnosis and treatment.