Hippocampal neurogenesis continues to occur well into old age, and in those with Alzheimer's disease. Researchers found evidence of neurogenesis in people up to the age of 99. While neurogenesis continues to occur in those with Alzheimer's disease, it is significantly reduced compared to those who have normal cognitive function.
Researchers discover the protein nestin produced in astrocytes plays a role in inhibiting neural differentiation. The study reports nestin does not control adult neurogenesis by acting within neural stem cells, but by regulating Notch signals neural stem cells receive from astrocytes.
Researchers say a novel enzyme treatment may reduce inflammation and scarring that prevents neural regeneration in spinal cord injury.
Researchers believe their findings could lead to new targets for brain cancer therapies.
Researchers transform iPSCs into neurons to test the efficacy of drugs to treat Alzheimer's disease.