Cocaine use disorder alters gene expression in the nucleus accumbens and caudate nucleus, brain areas associated with reward, and the mediation of habit formation.
Mice exposed to dust from the WTC showed impairments in both long and short-term memory, and spatial recognition, as well as alterations to genes associated with immune-inflammatory response and blood-brain barrier dysfunction. Findings suggest first responders who were exposed to dust from the WTC experience a peripheral-brain immune inflammatory response that leads to cognitive decline.
Study demonstrates two different types of deposits in the retina that appear to contribute to age-related macular degeneration.
People with subretinal drusenoid deposits (SDD), a form of age-related macular degeneration, are more likely to have underlying heart damage as a result of heart failure or heart attacks, or other forms of cardiovascular disease associated with increased stroke risk.
Neurons derived from stem cells of combat veterans with PTSD react differently to stress hormones than those derived from veterans without PTSD. The findings shed new light on how genetics can cause some to develop PTSD following a traumatic event.
Greater impairment of the prefrontal cortex-habenula pathway was correlated with earlier age of first drug use.
Sleep deprivation alters the structure of DNA inside immune cells and increases the number of immune cells, which causes them to overreact and spark inflammation. The study found catching up on sleep does not reverse this effect.
Researchers say Black patients are at greater risk of advanced vision loss than white patients following a diagnosis of primary open angle glaucoma.
Age-related macular degeneration with subretinal drusenoid deposits was associated with high-risk vascular diseases, including increased stroke risk and cardiovascular disease.
Researchers discovered both immune system and central nervous system dysfunction in animal models and people with ALS4, a genetic, juvenile, and slow-progressing form of ALS.
Study reveals how acute stress influences the brain's control over immune response, impacting recovery from COVID-19 and influenza.
Researchers have identified a neural mechanism that supports advanced cognitive functions such as planning and problem-solving. The mechanism distributes information from a single neuron to larger neural populations in the prefrontal cortex.
