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Mount Sinai Hospital

·May 21, 2020

ALS biomarker found in children’s teeth

Researchers have identified a new, early biomarker for amyotrophic lateral sclerosis (ALS) on the teeth of children. Patients who were diagnosed with ALS in adulthood showed signs of dysregulation uptake of a mixture of essential elements, including zinc, copper, lead, and tin, on their teeth. The study is the first to show clear signatures at birth and within the first decade of life for ALS. Read More

Featured Genetics Neuroscience Psychology

·April 22, 2020

Novel class of specific RNAs may explain increased depression susceptibility in females

Long non-coding RNAs (lncRNAs) are significantly altered in depression in both sex and brain site-specific manners. The LINC00473 gene is downregulated in the prefrontal cortex of depressed females, but not males. Findings reveal the role of LINC00473 in sex-specific depression and may explain why females are more vulnerable to depressive symptoms than males. Read More

Featured Genetics Neuroscience

·April 9, 2020

Novel role for dopamine that impacts gene expression related to cocaine abuse discovered

Reducing H3Q5dop in rat models of cocaine withdrawal significantly reversed cocaine mediated gene expression changes and reduced cocaine-seeking behaviors. Read More

Featured Neuroscience Open Neuroscience Articles Psychology

·February 23, 2020

Social isolation during adolescence drives long-term disruptions in social behavior

Social isolation during key periods of adolescence leads to long-term disruptions in social behavior and activity in neural patterns. Read More

Autism Featured Genetics Neuroscience

·January 23, 2020

Largest autism genetics study identifies 102 associated genes

In the largest genetic sequencing study of autism conducted to date, researchers have identified 102 genes associated with the neurodevelopmental disorder. 49 of the genes were also associated with other developmental delays. The new study has enabled the researchers to increase the number of ASD associated genes from 65 to 102. Read More

Featured Neuroscience Psychology

·October 5, 2019

Long-term study data shows DBS is effective treatment for most severe form of depression

Long term outcome data of patients with treatment-resistant depression found subcallosal cingulate deep brain stimulation (SCC DBS) was both effective at relieving symptoms and safe. Read More

Featured Neuroscience Open Neuroscience Articles Psychology

·October 2, 2019

The propensity to hear ‘voices’ in Schizophrenia may be established by infancy

People with schizophrenia who experience auditory hallucinations have greater activation in specific areas of the auditory cortex in response to sound frequencies. The mapping of sound frequency in the auditory cortex is scrambled in those with schizophrenia, suggesting a disruption in the normal processes for organized sound representation in the brain. As the tonotopic map is established during infancy and remains stable throughout life, the findings suggest vulnerability for auditory hallucinations is linked to defects in the organization of the auditory system during infantile development. This precedes speech development and the onset of psychiatric symptoms. Read More

Featured Genetics Neuroscience Psychology

·June 5, 2019

Individuals who attempt suicide carry an increased genetic liability for depression, regardless of their psychiatric disorder

A genetic liability for major depression increases suicide risk across other psychiatric disorders. Read More

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Featured Neuroscience Psychology

·May 21, 2019

CBD reduces craving and anxiety in people with heroin use disorder

CBD reduces craving and anxiety in those with heroin use disorder during withdrawal from the drug. There were no serious adverse reactions, or impairments to cognition noted with the administration of CBD. Researchers suggest cannabidiol may be useful in helping to combat opioid addiction. Read More

Autism Featured Genetics Neuroscience Psychology

·May 1, 2019

20 novel genes associated with bipolar disorder identified

A study of more than 50,000 patients with bipolar disorder in 14 countries helped researchers identify 20 new genetic risk factors for bipolar disorder. Eight of the genes also had an association with an increased risk for schizophrenia. ASD and anorexia, it was discovered, also had genetic ties to bipolar depression. Read More

Featured Genetics Neuroscience Psychology

·April 23, 2019

Short period of parental sexual contact prior to pregnancy increases offspring risk of schizophrenia

Study reports children born to couples who have been in relationships for three years or less may have an increased risk of schizophrenia. Read More

Brain Cancer Featured Genetics Neurology Neuroscience Open Neuroscience Articles

·January 14, 2019

Herpes Virus and Tumors Evolved to Learn How to Manipulate the Same Ancient RNA

A new study reports herpes virus utilizes ancient RNA to proliferate, mimicking the same process tumors have been found to manipulate. The findings could have implications for new treatment options and also may shed light on neurodegenerative diseases. Read More

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