Researchers have identified a bio-chemical circuit that supports neuron-microglia communication. When neurons are active, they release ATP. Microglia sense extracellular ATP and the compound draws the immune cell toward the neuron.
Researchers report computer based analysis of speech transcripts from teens at risk of psychosis were able to predict, with 83% accuracy, who would develop symptoms within 2 years.
Social isolation during key periods of adolescence leads to long-term disruptions in social behavior and activity in neural patterns.
According to a new study, cocaine has the most potent effects on the female brain when estrogen levels are at their highest.
Long term outcome data of patients with treatment-resistant depression found subcallosal cingulate deep brain stimulation (SCC DBS) was both effective at relieving symptoms and safe.
The risk of developing PTSD was eight times higher in teens who experienced traumatic events and had elevated acyl-ghrelin levels than trauma-exposed teens with lower levels of the hormone.
Short period of parental sexual contact prior to pregnancy increases offspring risk of schizophrenia
Study reports children born to couples who have been in relationships for three years or less may have an increased risk of schizophrenia.
Researchers discovered both immune system and central nervous system dysfunction in animal models and people with ALS4, a genetic, juvenile, and slow-progressing form of ALS.
Researchers have identified two compounds derived from grapes that might help to treat those with major depressive disorder.
Researchers have identified a neural mechanism that supports advanced cognitive functions such as planning and problem-solving. The mechanism distributes information from a single neuron to larger neural populations in the prefrontal cortex.
Researchers recreated the damage seen in frontotemporal dementia in brain organoid models. The study reveals an experimental drug designed to treat Crohn's disease may help prevent neuron death associated with FTD.
People with schizophrenia who experience auditory hallucinations have greater activation in specific areas of the auditory cortex in response to sound frequencies. The mapping of sound frequency in the auditory cortex is scrambled in those with schizophrenia, suggesting a disruption in the normal processes for organized sound representation in the brain. As the tonotopic map is established during infancy and remains stable throughout life, the findings suggest vulnerability for auditory hallucinations is linked to defects in the organization of the auditory system during infantile development. This precedes speech development and the onset of psychiatric symptoms.
