A study of more than 50,000 patients with bipolar disorder in 14 countries helped researchers identify 20 new genetic risk factors for bipolar disorder. Eight of the genes also had an association with an increased risk for schizophrenia. ASD and anorexia, it was discovered, also had genetic ties to bipolar depression.
Researchers have identified 64 genomic regions that contain genetic variants associated with an increased risk of developing bipolar disorder. The study also revealed a genetic overlap between bipolar disorder and other psychiatric disorders.
Researchers have discovered an elevated rate of language delay in 30 month old girls born to mothers who took the pain killer acetaminophen during pregnancy. The delay, however, was not witnessed in boys.
Researchers have identified a new, early biomarker for amyotrophic lateral sclerosis (ALS) on the teeth of children. Patients who were diagnosed with ALS in adulthood showed signs of dysregulation uptake of a mixture of essential elements, including zinc, copper, lead, and tin, on their teeth. The study is the first to show clear signatures at birth and within the first decade of life for ALS.
Ezogabine, an FDA approved anti-convulsant, appears to significantly reduce symptoms in those with major depressive disorder.
Researchers have identified a biomarker that can help predict a patient's prognosis and response to therapies for glioblastoma brain cancer subtypes.
Mothers who use cannabis during pregnancy to relieve stress may be putting their children at risk of developing anxiety and stress later in life. Researchers found placental tissue revealed cannabis use in mothers was associated with lower expression of immune-activating genes. Cannabis suppression of placental immune-gene networks predicted higher anxiety in children.
CBD reduces craving and anxiety in those with heroin use disorder during withdrawal from the drug. There were no serious adverse reactions, or impairments to cognition noted with the administration of CBD. Researchers suggest cannabidiol may be useful in helping to combat opioid addiction.
A new study reveals chronic cocaine users have a global impairment of the ventromedial prefrontal cortex.
Researchers reveal patients with inflammatory bowel disease are 28% more likely to develop Parkinson's disease. However, an anti-inflammatory treatment used to help those with IBD can significantly decrease the risk of developing the neurodegenerative disease.
Researchers recreated the damage seen in frontotemporal dementia in brain organoid models. The study reveals an experimental drug designed to treat Crohn's disease may help prevent neuron death associated with FTD.