An imbalance in gut bacteria can cause the reduction of some metabolites, resulting in depression-like symptoms. The findings contribute to the growing body of evidence for the role the microbiome plays in brain function and mental health.
Older people who have higher levels of neuroticism are more likely to have worse cognitive function than those with other personality traits. Researchers say personality traits may be related to how well people can maintain their cognitive function, despite developing neuropathology associated with aging and dementia.
During periods where personal choices of activities are constrained, natural mood regulation becomes impaired, resulting in an increased risk of depression.
Transcranial focused ultrasound (tFUS) can help elevate mood and decrease activity in brain networks associated with psychiatric disorders when directed at the ventrolateral prefrontal cortex.
Cannabis use in males appears to alter sperm before mating, increasing the risk of their offspring developing brain abnormalities in areas associated with mood, memory, learning, and reward.
Increased potassium currents were responsible for hyperactivity of CA3 neurons. When exposed to potassium channel blockers, the hyperactivity disappeared. However, when exposed to lithium, the drug not only reversed hyperactivity but reduced potassium currents at the same time. The findings strengthen the case that potassium currents play a role in bipolar disorder.
Binaural beats, a form of auditory illusion, caused far apart brain regions to synchronize with each other at a different frequency than the beat. The auditory illusion did not, however, alter mood.
Low-intensity exercise triggers brain networks associated with cognitive control and attention processing, while high-intensity exercise activates networks involved in emotional processing.
Psychedelics, such as psilocybin, provide lasting improvements in mood and feelings of social connectedness, after the effect of the drug has worn off.