Researchers have identified a set of drug-like compounds, including a common ingredient in throat lozenges, that can help protect mitochondria from the stresses associated with neurodegenerative diseases.
The ARHGAP11B protein located in mitochondria induces a metabolic pathway, similar to the characteristics of cancer cells, in brain stem cells, resulting in brain development.
Researchers tie some cases of sudden infant death syndrome (SIDS) with a genetic mutation that causes an inability to process milk, leaving the child vulnerable to sudden heart failure. Future studies will explore if a drug called Elamipretide can help reduce cardiac events in children with the mutation.
High-fat diets are not only bad for your waistline, they are also bad for your brain health. A new study reveals high-fat diets contribute to hypothalamic inflammation which occurs long before symptoms of obesity arise.
Mice infected with bacteria that cause mild intestinal infections exhibited Parkinson's like symptoms later in life. The findings provide a pathophysiological model in which intestinal infections may act as a trigger for Parkinson's disease.
Understanding the complexity of the human microbiome may help unlock mysteries behind health and psychological illnesses.
Ceramide exposure impairs the ability for neurons to make energy by directly damaging mitochondria. Additionally, ceramides force neurons to rapidly uptake glucose in order to provide cellular energy.
Mitochondrial CYP2D6 may be a powerful target for the treatment of Parkinson's disease induced by MPTP.
The MITOL protein has been implicated in Parkinson's disease.
Findings from a mouse model study reveal Miro2 functions as a platform for Parkin translocation and damaged mitochondrial clearance.
Mouse models of DiGeorge/22q1 Deletion Syndrome reveal a connection between mitochondrial dysfunction, deficits in cortical connectivity and cognitive impairments. Function was restored through antioxidant therapy.
Mitochondrial function may help explain the link between intelligence, general health and aging.
