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mitochondria

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Autism Featured Genetics Neuroscience

·February 1, 2021·2 min read

Defects in Mitochondria May Lead to Autism

Mitochondrial defects in brain cells may be a cause of autism spectrum disorder, a new study reports.

Brain Cancer Featured Genetics Neurology Neuroscience

·January 11, 2021·6 min read

One in Five Brain Cancers Fueled by Overactive Mitochondria

20% of glioblastoma brain cancers are fueled by overactive mitochondria. Researchers say these cases may be treatable by drugs currently under trial.

This shows the mitochondrial reprogrammed neurons

Featured Genetics Neuroscience

·November 17, 2020·4 min read

Researchers Improve Neuronal Reprogramming by Manipulating Mitochondria

Expressing neuron enriched mitochondrial proteins, researchers achieved a four times higher glial cell conversion rate and simultaneously increased the speed of neural reprogramming.

Brain Cancer Featured Neurology

·October 9, 2020·3 min read

Experimental Glioblastoma Therapy Shows Curative Powers

MP-Pt(IV), a second generation prodrug appears to have curative properties against glioblastoma when coupled with chemotherapy in mouse models.

Electrophysiology Featured Neuroscience

·October 5, 2020·3 min read

How the Brain May Fuel Intense Neural Communication

The retrieval of mitochondria via a feedback loop is vital to sustaining synaptic transmission.

Featured Neurology Neuroscience Open Neuroscience Articles

·August 31, 2020·3 min read

Neurons Protect Themselves From Degeneration by Adapting Their Metabolism

Neurons can counteract degeneration and promote survival by adapting their metabolism.

Featured Genetics Neuroscience

·August 13, 2020·4 min read

Becoming a Nerve Cell: Timing Is of the Essence

Mitochondria regulate how neural stem cells become neurons during brain development. The findings may help explain how humans developed larger brains during evolution and how mitochondrial defects lead to some neurodevelopmental disorders.

Featured Genetics Neurology

·July 22, 2020·6 min read

Neural Vulnerability in Huntington’s Disease Tied to Release of Mitochondrial RNA

In both human cell and mouse models of Huntington's disease, RNA from mitochondria was misplaced within spiny projection neurons. The stray RNAs, which looked different to cells than RNA derived from the cell nucleus, trigger an immune reaction that can lead to striatal cell type vulnerability.

Featured Neuroscience Psychology

·July 8, 2020·4 min read

Astrocytes Shed Light on the Link Between Cannabis Use and Sociability

Exposing mice to THC, researchers noted persistent activation of mitochondrial cannabinoid receptors located within astrocytes resulted in a cascade of molecular processing that led to dysfunctional glucose metabolism. The ability of astrocytes to transform glucose into "food" for neurons was reduced. The reduction resulted in a compromise in neural function, with a harmful impact on behavior. Specifically, social interactions were reduced for 24 hours post cannabis exposure.

Featured Genetics Open Neuroscience Articles

·June 24, 2020·5 min read

Protein in mitochondria appears to regulate health and longevity

Humanin, a peptide encoded in mitochondria, appears to have a beneficial impact on both health and longevity in both humans and animals. Higher levels of humanin in the body are associated with longer life spans and a reduced risk of neurodegenerative disorders, like Alzheimer's disease.

Featured Neurology Neuroscience

·March 3, 2020·4 min read

Boosting energy levels within damaged nerves may help them heal

Enhancing mitochondrial transportation and cellular energetics could help promote regeneration and function following spinal cord injury.

Electrophysiology Featured Genetics Neurology Neuroscience Open Neuroscience Articles

·January 12, 2020·4 min read

Neurons’ energy organelle protected from damage linked to ALS & Alzheimer’s

Researchers have identified a set of drug-like compounds, including a common ingredient in throat lozenges, that can help protect mitochondria from the stresses associated with neurodegenerative diseases.

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