People with untreated depression have lower levels of mitochondrial proteins. For those who responded to the SSRI antidepressants, the proteins returned to a normal level, but showed no increase in those who did not respond to medication.
Post-mortem studies of brain tissue from ALS patients reveal an abnormal form of tau is present in novel brain areas, and the tau interacts with DRP1. The tau appears to cause the brain cell's mitochondria to fragment and increase oxidative stress. Reducing tau reversed the effect, decreasing oxidative stress and mitochondrial fragmentation.
Microglia immune cells can join together to form networks when needed, a new study reports. However, certain mutations associated with Parkinson's disease can impair this process.
A new study on aging reveals a surprising discovery about the connection between protein shape and mitochondrial health.
An experimental small molecule helped restore the removal of mitochondria from dopamine-producing neurons in the brain. The findings may help in the development of new therapies for Parkinson's disease.
Sporadic Parkinson's disease appears to be caused by a blockage in the pathway that helps regulate mitochondria.
Study confirms stress can accelerate premature graying of hair, but there is hope. Reducing stress helps to restore some of your natural color.
Too much salt can disrupt the energy balance of immune cells and prevent them from functioning correctly.
Researchers have developed a new, non-invasive test to diagnose Parkinson's disease which relies on a simple skin swab. The test analyses sebum, the oily substance that coats and protects the skin. People with Parkinson's often have increased production of sebum. The researchers identified 10 compounds within sebum that were either elevated or reduced in people with Parkinson's.
Exercise promotes the hypothalamus to release MOTS-c. Mitochondrial encoded MOTS-c interacts with the nuclear genome and regulates both cell metabolism and the stress response.
Mitochondrial defects in brain cells may be a cause of autism spectrum disorder, a new study reports.
20% of glioblastoma brain cancers are fueled by overactive mitochondria. Researchers say these cases may be treatable by drugs currently under trial.
