Researchers have identified a set of drug-like compounds, including a common ingredient in throat lozenges, that can help protect mitochondria from the stresses associated with neurodegenerative diseases. Read More
The ARHGAP11B protein located in mitochondria induces a metabolic pathway, similar to the characteristics of cancer cells, in brain stem cells, resulting in brain development. Read More
Researchers tie some cases of sudden infant death syndrome (SIDS) with a genetic mutation that causes an inability to process milk, leaving the child vulnerable to sudden heart failure. Future studies will explore if a drug called Elamipretide can help reduce cardiac events in children with the mutation. Read More
High-fat diets are not only bad for your waistline, they are also bad for your brain health. A new study reveals high-fat diets contribute to hypothalamic inflammation which occurs long before symptoms of obesity arise. Read More
Mice infected with bacteria that cause mild intestinal infections exhibited Parkinson's like symptoms later in life. The findings provide a pathophysiological model in which intestinal infections may act as a trigger for Parkinson's disease. Read More
Understanding the complexity of the human microbiome may help unlock mysteries behind health and psychological illnesses. Read More
Ceramide exposure impairs the ability for neurons to make energy by directly damaging mitochondria. Additionally, ceramides force neurons to rapidly uptake glucose in order to provide cellular energy. Read More
Mitochondrial CYP2D6 may be a powerful target for the treatment of Parkinson's disease induced by MPTP. Read More
The MITOL protein has been implicated in Parkinson's disease. Read More
Findings from a mouse model study reveal Miro2 functions as a platform for Parkin translocation and damaged mitochondrial clearance. Read More
Mouse models of DiGeorge/22q1 Deletion Syndrome reveal a connection between mitochondrial dysfunction, deficits in cortical connectivity and cognitive impairments. Function was restored through antioxidant therapy. Read More
Mitochondrial function may help explain the link between intelligence, general health and aging. Read More
