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mitochondria

Featured Genetics Neurology Neuroscience

·May 16, 2024·7 min read

Mitochondrial Boost Reverses Protein Clumping in Aging and Alzheimer’s

A new study in worms reveals a core set of insoluble proteins linked to both aging and Alzheimer's disease. These proteins accumulate during normal aging and are exacerbated by amyloid beta, a hallmark of Alzheimer's.

Featured Neuroscience

·April 25, 2024·4 min read

Sight and Smell of Food Kickstarts Liver Activity

Merely seeing and smelling food can activate adaptations in liver mitochondria in mice within minutes. This response is driven by the activation of POMC neurons in the brain, signaling the liver to prepare for nutrient processing by modifying mitochondrial protein through phosphorylation.

Featured Genetics Neurology Neuroscience

·April 5, 2024·4 min read

Powering Brain Repair: Mitochondria Key to Neurogenesis

Researchers made a groundbreaking discovery about the maturation process of adult-born neurons in the brain, highlighting the critical role of mitochondrial fusion in these cells. Their study shows that as neurons develop, their mitochondria undergo dynamic changes that are crucial for the neurons' ability to form and refine connections, supporting synaptic plasticity in the adult hippocampus.

Featured Genetics Neuroscience

·February 8, 2024·6 min read

Mitochondrial Transport Key to Neurological Health

Researchers have discovered a molecular complex crucial for the transport of mitochondria within neurons, offering new insights into preventing neurodegenerative diseases. The complex, identified as Alex3/Gαq, is pivotal for distributing energy-producing mitochondria throughout neurons, essential for neurotransmission and neuronal functions.

Featured Genetics Neuroscience

·January 29, 2024·5 min read

Gene Linked to Mitochondrial Dysfunction in Obesity

Researchers made a breakthrough in understanding obesity's impact on mitochondria, as detailed in a recent study. They discovered that a high-fat diet causes fat cell mitochondria in mice to fragment into smaller, less efficient units, a process controlled by a single gene.

Featured Genetics Neuroscience Psychology

·August 21, 2023·5 min read

Unlocking Schizophrenia: Mitochondria Dysfunction at the Forefront

Researchers have identified a pivotal role of impaired mitochondrial function in the development of schizophrenia by examining the genetic risk factor 3q29 deletion syndrome. The genetic condition, known to amplify schizophrenia risk by 40 times, displayed alterations in mitochondrial activity in both mice models and human brain organoids.

Featured Genetics Neuroscience

·July 25, 2023·5 min read

Slowing Down the Clock: Key Discovery in Aging and Chronic Inflammation

Researchers uncovered a key mechanism of aging - improper calcium signaling in the mitochondria of certain immune cells, leading to chronic inflammation. As we age, these mitochondria in macrophages lose their ability to uptake and utilize calcium, contributing to various age-related conditions.

This shows a brain in the style of Van Gogh

Featured Neurology Neuroscience

·March 13, 2023·4 min read

A New Immune Pathway Sheds Light on ALS

A recent study reveals that certain proteins, usually associated with inflammation and immunity, can cause damage to our neurons, contributing to ALS.

Featured Neuroscience Visual Neuroscience

·March 10, 2023·3 min read

Therapeutic Target for Glaucoma Discovered

Restoring mitochondrial homeostasis in diseased neurons can protect the optic nerve from being damaged and potentially reverse symptoms of glaucoma.

Featured Genetics Neuroscience Psychology

·February 7, 2023·3 min read

Mitochondrial Deterioration Linked to Major Depression in Older Adults

In older adults, major depression has been linked to mitochondrial deterioration.

Featured Neuroscience

·January 30, 2023·3 min read

Antioxidants From Mitochondria Protect Cells From Dying

The STARD7 enzyme helps transport the antioxidant coenzyme Q from the mitochondria to the cell surface.

Featured Neuroscience Open Neuroscience Articles

·January 15, 2023·5 min read

Overactive Cell Metabolism Linked to Biological Aging

Human cells with impaired mitochondria expend more energy. While this hypermetabolism enhances a cell's short-term survival, it also dramatically increases the rate at which the cell ages.

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mitochondria

Mitochondrial Boost Reverses Protein Clumping in Aging and Alzheimer’s

Sight and Smell of Food Kickstarts Liver Activity

Powering Brain Repair: Mitochondria Key to Neurogenesis

Mitochondrial Transport Key to Neurological Health

Gene Linked to Mitochondrial Dysfunction in Obesity

Unlocking Schizophrenia: Mitochondria Dysfunction at the Forefront

Slowing Down the Clock: Key Discovery in Aging and Chronic Inflammation

A New Immune Pathway Sheds Light on ALS

Therapeutic Target for Glaucoma Discovered

Mitochondrial Deterioration Linked to Major Depression in Older Adults

Antioxidants From Mitochondria Protect Cells From Dying

Overactive Cell Metabolism Linked to Biological Aging

Young Adult Substance Use Affects Memory at 65

Nicotine Vapes Outperform Patches and Gum for Quitters

Split Protein Builds the Infrastructure for Weight Loss

Can Deep Brain Stimulation Unlock Treatment-Resistant Depression?

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