Clues to Brain Differences Between Males and Females
A new study reveals how male sex steroids impact brain development. The findings could help shed light on behavioral developmental differences between males and females.... Read More...
microglia
Can a Nerve Injury Trigger ALS?
A new study reveals peripheral nerve damage may trigger the onset and spread of ALS in mouse models of the neurodegenerative disease.... Read More...
Young Bone Marrow Rejuvenates Aging Brains: Mouse Study
Researchers report transplanting bone marrow from young mice to older mice helps to preserve memory and learning skills. If the findings can be replicated in humans, researchers believe new therapies can be devised to help combat disorders associated with brain aging.... Read More...
Researchers Create New Map of Brain’s Immune System
Researchers have successfully created a new map of the brain's immune system in both mice and humans. The findings suggest microglia all have the same core signatures, but can act differently, depending on their function. The map also details how the brain's immune system changes as multiple sclerosis progresses.... Read More...
New Scan Technique Reveals Neuroinflammation Associated with Post-Treatment Lyme Disease Syndrome
A new neuroimaging study reveals 12 people with documented post-treatment Lyme disease syndrome have an elevation of a chemical marker associated with neuroinflammation. The findings could help develop new treatments for the pain, fatigue and brain fog associated with PTLDS.... Read More...
Excess Immune Pruning of Synapses in Neural Cells Derived From Patients with Schizophrenia
Researchers have directly observed excessive synaptic pruning in cells derived from people with schizophrenia.... Read More...
New Genetic Risk Factor for Alzheimer’s Disease
A new study reveals a novel genetic risk loci for Alzheimer's disease. Using single cell gene expression patterns, researchers found genetic changes are expressed in microglia cells. The mutations are associated with an increased risk of Alzheimer's disease.... Read More...
Defective Immune Cells in Brain May Cause Alzheimer’s
Researchers report therapeutic activation of the TREM2 gene during the early stages of Alzheimer's disease may help to counteract the formation of amyloid beta protein aggregates.... Read More...
Fungi Causes Brain Infection and Memory Impairments: Mouse Study
Researchers report a common yeast infection can cross the blood-brain barrier, triggering an inflammatory response that results in the formation of granuloma type structures and temporary memory impairments in mice. ... Read More...
Microglia React Distinctly During Inflammation
A new study sheds light into the function of microglia and inflammatory response.... Read More...
Regulating Microglial Activity May Reduce Inflammation in Neurodegenerative Diseases
Researchers report activating microglia may help reduce the imbalance between neuroprotection and neurotoxicity for neurodegenerative diseases.... Read More...
Widespread Inflammation in Brains of Those with Fibromyalgia
A new study reveals elevated glial activation in the brains of those with fibromyalgia.... Read More...