Microglia appear to play a key role in inflammation-associated depression. Read More
Disruptions in circulating white blood cells may be a key driver in ALSP, a rare form of early-onset dementia. Read More
Changes in fetal microglia caused as a result of maternal inflammation could contribute to the development of schizophrenia, autism, and other psychiatric or developmental disorders. Read More
Astrocytes, not microglia, are responsible for constantly eliminating unnecessary and excessive adult synaptic connections in response to brain activity. Read More
Study identifies a pathway involving astrocytes that help explain why some with multiple sclerosis experience seizures. Read More
YKL-40 may be a key player in circadian rhythm disruptions associated with Alzheimer's disease. Read More
Microglia cells continuously survey the brain to help prevent sporadic seizures. Read More
Recovery from multiple sclerosis-like symptoms in mice depends upon the ability for microglia to break down the remains of damaged cells. Read More
Researchers have identified a bio-chemical circuit that supports neuron-microglia communication. When neurons are active, they release ATP. Microglia sense extracellular ATP and the compound draws the immune cell toward the neuron. Read More
PLCG2-P522R, a genetic variant that protects against Alzheimer's disease, enhances key functions of immune cells. Read More
Study identifies a specific type of immune cell that induces inflammation in herpes simplex virus (HSV) encephalitis. Read More
Microglia, immune cells that protect the brain from infection and inflammation, also appear to play a critical role in sculpting circuits in the developing brain. Read More
