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MCI

·September 2, 2020·6 min read

Common Drugs Tied to Increased Risk of Cognitive Decline

Anticholinergic medications, commonly used for conditions including allergies, high blood pressure, Parkinson's disease, and motion sickness, have been linked to an increased risk of cognitive decline and memory problems, especially in those with genetic risk factors for Alzheimer's disease.

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·August 31, 2020·3 min read

Fungi in Gut Linked to Higher Alzheimer’s Risk Can Be Reduced Through Ketogenic Diet

Following the Mediterranean ketogenic diet can help modulate unique fungi found in the gut of those with mild cognitive impairment.

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·July 31, 2020·4 min read

Memory Loss Reversed or Abated in Those With Cognitive Decline

Study reports success in treating cognitive decline and memory loss associated with Alzheimer's disease with the aid of personalized precision medicine.

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·July 29, 2020·3 min read

Are Your Gums Saying Something About Your Dementia Risk?

22% of study participants with severe gum disease developed dementia, and 23% diagnosed with mild cognitive impairment suffered extreme tooth loss. Only 14% of those with healthy gums were later diagnosed with the neurodegenerative disorder. The findings add further evidence for the link between dental hygiene and dementia.

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·June 3, 2020·2 min read

Certain personality traits may affect risk of ‘pre-dementia’

Certain personality traits could increase the risk of developing mild cognitive impairment, a new study reports. Openness was associated with a 6% reduced risk of developing a pre-dementia condition, while those who scored higher for neuroticism had a 6% increased risk of MCI.

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·March 25, 2020·4 min read

An aspirin a day does not keep dementia at bay

Contrary to popular belief, taking a low-dose of aspirin daily does not reduce the risk of developing mild cognitive impairment (MCI). Researchers found no difference between older people who took aspirin and those who took a placebo in the risk of developing MCI, dementia, or Alzheimer's disease.

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·February 13, 2020·3 min read

Can bilingualism protect the brain even with early stages of dementia?

While being bilingual delays the onset of dementia, the decline into full-blown Alzheimer's disease is more rapid in those who speak two or more languages than in monolingual people.

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·January 1, 2020·5 min read

Objective subtle cognitive difficulties predict amyloid accumulation and neurodegeneration

Amyloid accumulation occurs faster in those who have objectively-defined cognitive difficulties than older people who are considered to be cognitively normal. Mild cognitive impairment is also associated with faster hippocampal and entorhinal cortex atrophy.

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·December 30, 2019·3 min read

What comes first, beta-amyloid plaques or thinking and memory problems?

Subtle changes in thinking and memory may appear before, or in conjunction with, the development of amyloid plaques.

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·December 29, 2019·7 min read

Drugs that quell brain inflammation reverse dementia

Older mice given anti-inflammatory medication were better able to learn new tasks and became almost as adept at learning as mice half their age.

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·December 4, 2019·6 min read

Drugs that quell brain inflammation reverse dementia

A synthesized small-molecule drug blocks the TGF-beta receptor in astrocytes and traverses the blood-brain barrier in mice. When administered, the drug lowered receptor activity to that seen in younger mice and reduced inflammation. The aged mice were able to navigate mazes and learn spatial tasks as well as younger mice.

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·November 29, 2019·5 min read

Aerobic exercise and heart-healthy diet may slow development of memory problems

Combining aerobic exercise with the heart-healthy DASH diet improved the ability to think, recall, and make decisions in older people who experienced cognitive decline and mild cognitive impairment.