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major depressive disorder

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·December 3, 2019·4 min read

Imaging reveals pathways behind depression

Two new neuroimaging studies shed light on structural and functional abnormalities in the brains of those with major depressive disorder.

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·November 18, 2019·4 min read

Side effects mild and brief with single antidepressant dose of intravenous ketamine

The side effects of administering ketamine to treat major depressive disorder are mild and persist for no longer than four hours, researchers report. Most of the side effects peaked within an hour of treatment, and many patients reported the effects as being significantly reduced two hours post ketamine administration.

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·October 28, 2019·6 min read

Who will get depressed under major stress? Study shows promise of genetic risk prediction

A polygenetic risk score for major depressive disorder may reveal those most at risk of developing depression during times of extreme stress.

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·October 10, 2019·6 min read

Neurofeedback increases self-esteem by re-balancing brain circuits in depression

Neurofeedback training can alter guilt-related networks and improve self-esteem in those with major depressive disorder.

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·October 5, 2019·5 min read

Long-term study data shows DBS is effective treatment for most severe form of depression

Long term outcome data of patients with treatment-resistant depression found subcallosal cingulate deep brain stimulation (SCC DBS) was both effective at relieving symptoms and safe.

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·September 30, 2019·4 min read

People with anxiety may strategically choose worrying over relaxing

Those with anxiety and depressive disorders may actively resist relaxation, especially if they are more sensitive to shifts in negative emotions.

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·August 28, 2019·4 min read

Many psychiatric disorders have heightened impulsivity

The largest delay discounting effects were found to be associated with bipolar disorder, borderline personality disorder, and schizophrenia. The image is in the public domain.

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·August 1, 2019·3 min read

Brain activity may help predict success of CBT in depression

Only 45% of patients with major depressive disorder find benefit from cognitive behavioral therapy (CBT). A neuroimaging study reveals those who respond to CBT have greater neural activity in the right striatum and right amygdala pretreatment than those who find little benefit from the treatment. The findings could serve as a biomarker to discover who will respond to CBT.

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·July 27, 2019·3 min read

Genes underscore five psychiatric disorders

Nineteen gene sets have been identified that contribute to at least five psychiatric disorders. The gene sets were associated with ADHD, ASD, bipolar disorder, major depressive disorder, and schizophrenia.

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·July 23, 2019·6 min read

Obstructive sleep apnea may be one reason depression treatment doesn’t work

A potential link has been identified between obstructive sleep apnea (OSA) and major depressive disorder. Treating OSA may help to improve depressive symptoms, as well as reduce suicidal thoughts and improve sleep for those with insomnia.

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·June 18, 2019·3 min read

Antidepressants can reduce ’empathic empathy’

Antidepressants for major depressive disorder reduce the aversive response triggered by exposure to the suffering of others. Findings suggest antidepressants may lead to impaired empathy of pain perception.