Ezogabine, an FDA approved anti-convulsant, appears to significantly reduce symptoms in those with major depressive disorder.
A new study reports aerobic exercise can have antidepressant effects for patients with major depressive disorder.
According to researchers, a small cohort of MDD patients had significant improvements in sleep quality and reduced daytime sleepiness following treatment with the antidepressant Vortioxetine.
Researchers report the hypothalamus is, on average, five percent larger in those with mood disorders like major depressive disorder and bipolar disorder, than it is in those without depression.
Researchers report ketamine's antidepressive effects require activation of opioid receptors in the brain. The study highlights the interaction between depression, pain and opioid addiction.
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Researchers have developed a new machine learning algorithm which is 94% accurate in predicting which patients with complex mood disorders will respond to medications.
A new study reports patients with major depressive disorder and treatment resistant depression have decreased levels of acetyl-L-carnitine in their blood. The findings could lead to new blood tests to diagnose the nature and severity of depression.
Researchers have identified genetic overlaps between different types of psychiatric disorders including ADHD, bipolar disorder, MDD and schizophrenia. They also identified an overlap between anorexia and OCD, as well as between Tourettes and OCD.
Researchers have identified the role Klf9 plays in the brain's response to stress. The study reports elevated levels of the protein were discovered in the hippocampus of women with MDD who faced stressful events.
Researchers have developed a new computational model of major depressive disorder. The model reveals older memories, as well as short term memories, are affected by major depressive disorder. Researchers say how long the memory deficits go back depends on how long the depressive episode lasts.