Researchers have identified a layer of genetic material involved in controlling the production of tau in the brain. The material is part of a larger family of non-coding genes that regulate and control other brain proteins associated with neurodegenerative disorders, such as Alzheimer's disease, Parkinson's, and PSP. The findings could lead to the development of new therapeutics to treat a range of neurodegenerative disorders.
Long non-coding RNAs (lncRNAs) are significantly altered in depression in both sex and brain site-specific manners. The LINC00473 gene is downregulated in the prefrontal cortex of depressed females, but not males. Findings reveal the role of LINC00473 in sex-specific depression and may explain why females are more vulnerable to depressive symptoms than males.
Researchers discover similar signature molecular abnormalities in the brains of people with ASD.
Researchers report they have uncovered a gene responsible for brain development and also discovered how it may work.
Pnky, an RNA molecule, can be manipulated to increase the production of neurons from neural stem cells, a new study reports.
Researchers discover a role for long noncoding RNA in brain development and neurodegenerative diseases.