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Karolinska Institute

Auditory Neuroscience Featured Genetics Neuroscience

·April 27, 2025·4 min read

Tracing the Origins of Hearing

Researchers have developed a genetic "barcoding" method to trace how stem cells in embryos become neurons and inner ear cells. By labeling early stem cells in mice, the team followed their development and mapped the formation of the inner ear.

Featured Neurology Neuroscience

·March 11, 2025·5 min read

How a Common Virus Triggers Brain Attacks in Multiple Sclerosis

New research highlights a critical link between antibodies produced against Epstein-Barr virus (EBV) and the development of multiple sclerosis (MS). Scientists discovered that these viral antibodies mistakenly target a protein called GlialCAM in the brain, triggering autoimmune responses associated with MS.

Featured Neuroscience Psychology

·February 25, 2025·3 min read

SSRIs May Speed Up Cognitive Decline

A new study based on data from 18,740 dementia patients suggests that antidepressants may accelerate cognitive decline. Researchers found that patients taking antidepressants, particularly SSRIs like escitalopram, citalopram, and sertraline, experienced faster deterioration compared to those not on medication.

Featured Neuroscience Visual Neuroscience

·February 21, 2025·4 min read

Every Breath You Take Alters Your Visual Perception

Researchers have discovered that breathing affects pupil size, with the pupil being smallest during inhalation and largest during exhalation. This newly identified mechanism is independent of external stimuli and could influence vision by alternating between detail enhancement and object detection.

Featured Neurology Neuroscience

·December 20, 2024·5 min read

AI Estimates Brain Age, Links Lifestyle to Cognitive Health

Researchers used AI to analyze brain images from 70-year-olds, estimating their biological brain age and uncovering connections to lifestyle and health factors. Diabetes, inflammation, and high glucose levels were linked to older-looking brains, while regular exercise and healthy habits were associated with younger-looking brains.

Electrophysiology Featured Neuroscience

·December 4, 2024·4 min read

Your Heart’s Secret: It Has Its Own Nervous System

New research reveals the heart has its own complex nervous system, or "mini-brain," capable of regulating the heartbeat independently of the brain. Conducted on zebrafish, the study identified specialized neurons within the heart, including some with pacemaker properties, challenging traditional views of heartbeat control.

Featured Neurology Neuroscience Psychology

·December 3, 2024·3 min read

Empathy Loss in Dementia Linked to Brain Activity Changes

Frontotemporal dementia, affecting about 3% of dementia patients in Sweden, is characterized by a loss of empathy that challenges patients and their families. Using functional MRI, researchers found that patients showed no activation in brain networks associated with empathy when viewing distressing images, unlike healthy individuals.

Featured Genetics Neuroscience

·November 22, 2024·3 min read

3D RNA Imaging Revolutionizes Brain Research

Researchers have developed TRISCO, a cutting-edge microscopy method that enables 3D RNA analysis in whole, intact mouse brains without slicing them into sections. TRISCO reveals RNA molecules’ spatial distribution, providing unprecedented insights into the brain’s complex structure and function.

Featured Genetics Neuroscience Pain

·October 7, 2024·3 min read

Genetic Mapping Unlocks Path to Effective Chronic Pain Relief

Researchers have developed a comprehensive atlas that maps genetic activity in nerve cells linked to chronic pain, offering a potential breakthrough in non-addictive treatments. The study highlights key pain-sensitive nerve cell states, allowing for new therapeutic targets, such as senescent cells. Administering senolytic treatments in mice led to full recovery from pain without side effects, providing hope for chronic pain patients.

Featured Neuroscience Psychology

·September 4, 2024·5 min read

No Link Found Between Ozempic and Suicide Risk

A new study has found no evidence that GLP-1 analogues, common diabetes drugs, increase the risk of suicide, self-harm, or related mental health issues. Researchers analyzed data from around 300,000 people treated with these medications and found no clear link between the drugs and mental health risks.

Featured Neurology Neuroscience Pain

·August 30, 2024·3 min read

Morphine’s Pain Relief Mechanism Unveiled

Researchers have uncovered how morphine relieves pain by activating a specific group of neurons in the brain, termed the 'morphine ensemble.' These neurons, located in the rostral ventromedial medulla (RVM), connect to the spinal cord and inhibit pain signaling. Understanding this pathway could help reduce the severe side effects of morphine, such as addiction and overdose. The findings also provide insights into the differences between pain relief and the euphoric effects of morphine.

Autism Featured Neuroscience

·August 19, 2024·5 min read

AI Model Predicts Autism in Toddlers with 80% Accuracy

A new machine learning model, AutMedAI, can predict autism in children under two with nearly 80% accuracy, offering a promising tool for early detection and intervention. The model analyzes 28 parameters available before 24 months, such as age of first smile and eating difficulties, to identify children likely to have autism. Early diagnosis is crucial for optimal development, and further validation of the model is underway.

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