Karolinska Institute

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Karolinska Institute

Featured Neuroscience Open Neuroscience Articles Psychology

·October 2, 2020·4 min read

New Clues About the Link Between Stress and Depression

p11, a protein implicated in serotonin function, affects the initial release of cortisol in mice by modulating the activity of specific neurons in the hypothalamus. Previous studies found people with depression lave lower levels of p11 in their brains. The findings could help in the development of new treatments for depression and stress. Read More

Featured Neurology

·October 1, 2020·3 min read

Stem Cells Can Help Repair Spinal Cord After Injury

Research shows it is possible to stimulate stem cells in the spinal cord to produce large amounts of new oligodendrocytes. Read More

Autism Featured Neuroscience Open Neuroscience Articles

·September 9, 2020·4 min read

Imagery Reveals Autism-Related Brain Differences

People on the autism spectrum have lower levels of a protein that regulates serotonin in the brain. Read More

Autism Featured

·August 31, 2020·4 min read

Flu Vaccination in Pregnant Women Did Not Increase Risk of Autism

Study refutes any association between the H1N1 vaccine given to pregnant women and an increased risk of autism diagnosis in children. Read More

Featured Neurology Neuroscience Open Neuroscience Articles

·August 31, 2020·3 min read

Neurons Protect Themselves From Degeneration by Adapting Their Metabolism

Neurons can counteract degeneration and promote survival by adapting their metabolism. Read More

Featured Genetics Neuroscience Open Neuroscience Articles

·August 23, 2020·3 min read

Study Reveals the Unfolding of Neuronal Fate

Study combines developmental neurobiology and computational neuroscience to explore the dynamic changes of gene expression at the single-cell level as progenitor cells differentiate into neurons, then diversify into different sensory neurons. Read More

Featured Neuroscience Open Neuroscience Articles Psychology

·June 1, 2020·4 min read

How ketamine combats depression

Ketamine increases the number of serotonin 1B receptors. Ketamine binds to serotonin 1B receptors, reducing the release of serotonin and increasing the release of dopamine. Read More

This shows the shadow of a man in a tunnel

Featured Neuroscience Open Neuroscience Articles Psychology

·April 29, 2020·5 min read

Drug reduces risk of pedophiles re-offending

Degarelix, a drug that reduces testosterone levels, shows potential in the treatment of pedophilic disorder. Men with a history of child sexual abuse who took the drug had reduced overall sexual desire and decreased attraction toward children, with noticeable effects within two weeks. Read More

Featured Genetics Neurology Neuroscience

·April 27, 2020·3 min read

More evidence Parkinson’s disease may start in the gut

Enteric neurons appear to play a key role in the development of Parkinson's disease. The findings support the hypothesis and previous studies that the neurodegenerative disease may start in the gut before spreading to the brain. Researchers also found oligodendrocytes were affected during the early stages of Parkinson's, even before the loss of dopaminergic neurons. Read More

Featured Neuroscience Open Neuroscience Articles

·April 2, 2020·4 min read

Trial drug may block early stages of COVID-19, human cell study shows

hrsACE2, a genetically modified protein already being tested to prevent lung disease, reduces the viral growth of SARS-CoV-2 by a factor of 1,000 to 5,000 in human cell cultures. Researchers believe the enzyme copy lures the virus to attach itself to the copy, rather than human lung cells. The findings suggest hrsACE2 could significantly block the early stages of SARS-CoV-2 infections and prevent COVID-19 from becoming severe. Read More

This shows an apartment building next to a smoke stack

Featured Neurology Neuroscience Open Neuroscience Articles

·March 30, 2020·4 min read

Air pollution linked to dementia and cardiovascular disease

Long-term air pollution exposure was associated with a higher risk of dementia. Ischemic heart disease and heart failure appeared to enhance the link between air pollution and dementia. Read More

Featured Neuroscience Open Neuroscience Articles

·March 23, 2020·4 min read

COVID-19 pandemic likely to go in waves

A new mathematical model shows the current COVID-19 pandemic could decline during the summer months, but return in the fall, with a major resurgence next winter. The model takes into account the seasonal variations of other closely related respiratory coronaviruses. Based on other coronavirus data, the model reveals infections were ten times more common between December and April in the northern hemisphere than between July and September. Researchers emphasize this model only attempts to examine possible scenarios, as we are currently unsure how warmer temperatures will affect SARS-CoV-2. Read More

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