NPGL, a recently discovered protein, influences fat storage in the human body, even when on a calorie restricted diet. Researchers believe this mechanism had evolutionary benefits and the protein could be a potential target to treat obesity.
Researchers report the brain's ability to sense insulin and coordinate feeding with energy expenditure is controlled by a mechanism that is turned on after fasting to inhibit insulin response and conserve energy. After feeding, the mechanism is turned off to facilitate insulin response and expend energy. However, in obese people, researchers believe the switch may stay on all the time.
A new study reports insulin resistance is linked to accelerated cognitive decline.
In early Alzheimer's, glycation damages an enzyme that plays a crucial role in immune response and insulin regulation, researchers report.
Researchers have discovered a possible new treatment for Alzheimer's disease after noticing the way in which insulin signaling works in the brains and pancreas of diabetic patients.
A new study reports sleep loss can lead to alterations in gut bacteria that have previously been linked to diabetes and obesity in humans.
Researchers believe they might have identified a new abnormality in the relationship between dopamine and response to food in those with obesity.
Researchers report hundreds of genes that affect neurological function can be damaged by fructose. However, it may be possible to reverse some of the changes by adopting a diet rich in DHA.