A new paper describes the development of a cAMP analogue which specifically activates only Epac2.
Finding could point the way to new therapies to extend life and enhance healthy aging in humans.
According to a new study, diabetic episodes of hypoglycemia may increase the risk of developing dementia, while having dimentia could increase the risk of experiencing low blood sugar levels.
Soybean oil, the most consumed cooking oil in the US, has been linked to neurological and metabolic alterations in mice. Soybean oil-fed mice showed decreased levels of oxytocin in the hypothalamus.
According to researchers, people with diabetes may be at increased risk of suffering from depression as a result of biological problems in regulating sugar levels that influence emotional response in the brain. Using EEG, researchers discovered those with higher levels of insulin resistance showed greater response to negative images.
Researchers report keeping levels of KYNA low throughout a worm's life can help prevent the onsite of age-related cognitive decline.
Study sheds light on the role brain insulin plays in weight and visceral fat accumulation.
The absence of a specific type of neuron in the brain can lead to obesity and diabetes in mice report researchers. The outcome, however, depends on the type of diet that the animals are fed.
Researchers report the brain's ability to sense insulin and coordinate feeding with energy expenditure is controlled by a mechanism that is turned on after fasting to inhibit insulin response and conserve energy. After feeding, the mechanism is turned off to facilitate insulin response and expend energy. However, in obese people, researchers believe the switch may stay on all the time.