Researchers report leukemia undercuts the normal ability of cells to consume glucose, leaving more glucose available to help feed the growth of cancer cells.
Insulin signaling plays a role in regulating synaptic function, glucose homeostasis, and cognition, a new study reports. Impairments in insulin signaling result in metabolic defects, in addition to memory and learning deficits, mirroring the cognitive impairments associated with Alzheimer's disease.
Study reveals a link between amyloid-beta accumulation in the brain and lower levels of insulin and insulin resistance.
A variant of the CHC22 gene evolved to help people adapt to the modern, higher sugar diet. However, many people still retain the older version of the genetic variant, which does not allow for correct metabolism of modern diets and may be linked to an increased risk of developing diabetes.
NPGL, a recently discovered protein, influences fat storage in the human body, even when on a calorie restricted diet. Researchers believe this mechanism had evolutionary benefits and the protein could be a potential target to treat obesity.
Researchers debate the roles of the gut and brain hormones play in regulating appetite and metabolism.
Soybean oil, the most consumed cooking oil in the US, has been linked to neurological and metabolic alterations in mice. Soybean oil-fed mice showed decreased levels of oxytocin in the hypothalamus.
The absence of a specific type of neuron in the brain can lead to obesity and diabetes in mice report researchers. The outcome, however, depends on the type of diet that the animals are fed.
Finding could point the way to new therapies to extend life and enhance healthy aging in humans.
Islets of Langerhans in overnourished infant mice showed epigenetic profiles resembling those of much older mice.
The insulin-like growth factor II gene plays a critical role in adult stem cell maintenance of both the intestine and the brain. Findings suggest IGF-2 is essential for multiple stem cell types, including those implicated in cognitive function and renewing the lining of the small intestine.
Surfen, a compound molecule used for drug delivery of insulin could block tumor growth for patients with glioblastoma brain cancer.
