Researchers say the Huntingtin gene affects brain development from an early age, even though most patients do not develop Huntington's disease until later life.
Researchers have identified a mechanism that may reduce the toxic aggregation of the huntingtin protein. The findings could lead to new treatment options for Huntington's patients.
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Researchers have identified a reduced exchange of glutamine between astrocytes and neurons in a new Huntington's disease study.
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Researchers shed light on what happens to specific neurons when neurodegenerative diseases impact movement. The findings could help in the development of new treatments for Parkinson's and Huntington's disease.
Researchers have identified a genetic overlap between rheumatoid arthritis and Huntington's disease. The findings could open the door to developing new therapeutic targets and medications to combat both conditions.
Researchers have identified an over accumulation of iron in the mitochondria of mice genetically engineered to have Huntington's disease.
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Researchers have developed a new method that allows them to see how astrocytes influence neural communication in real time.
Gene expressions in the brain that occur early in development may explain why some cerebellar stem cell populations behave differently in people with SCA1, researchers report.
Restricting access to food within a strict time frame stimulates autophagy and lowers levels of the huntingtin protein in the brain, a new mouse study reveals.
A new study reports researchers have developed a new gene editing approach that may provide a new treatment avenue for Huntington's disease.
Researchers have decoded the 3D structure of the Huntingtin protein. The discovery may help develop new treatments for Huntington's disease.
Rockefeller University researchers reveal Huntington's neurons are much larger than healthy cells.