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          huntingtin

          This shows neurons
          FeaturedGeneticsNeurologyNeuroscience
          ·December 12, 2022·4 min read

          CRISPR Technology Improves Huntington’s Disease Symptoms in Models

          Using CRISPR gene editing to directly target RNA, researchers eliminated toxic protein buildup associated with Huntington's disease while not disrupting other human genes.
          Read More
          This shows a brain
          FeaturedGeneticsNeuroscienceOpen Neuroscience ArticlesPsychology
          ·December 1, 2022·4 min read

          Rare Genetic Phenomenon Linked to Neuron Function and Schizophrenia

          People with schizophrenia have significantly higher rates of tandem repeats in their genome, up to 7% more than in people without the mental health disorder. The genes were primarily found in genes crucial to brain function.
          Read More
          This shows a neuron
          FeaturedGeneticsNeurologyNeuroscience
          ·September 27, 2022·4 min read

          Study Probes Huntington’s Disease Protein’s Function in Injured Neurons

          The Huntington's disease protein huntingtin may have a role external to the neurodegenerative disease. Researchers say Huntingtin is involved in neural injury and regeneration.
          Read More
          This shows a cluster of cells
          FeaturedNeurologyNeuroscience
          ·October 5, 2021·4 min read

          Study Detects Origins of Huntington’s Disease in Two-Week-Old Human Embryos

          Synthesizing a human embryo from stem cells and using gene editing to insert the Huntingtin gene, researchers found the mutation affected the size of germ layers compared to the control embryos. Findings suggest Huntington's disease may be a neurodevelopmental disorder that presents as a neurodegenerative disease later
          Read More
          This shows neurons. The caption best describes the image
          FeaturedGeneticsNeurologyOpen Neuroscience Articles
          ·March 6, 2021·4 min read

          Huntington’s Disease Driven by Slowed Protein-Building Machinery in Cells

          The mutated huntingtin protein slows ribosome movement and decreases protein synthesis.
          Read More
          This shows DNA
          FeaturedGeneticsNeurologyNeuroscience
          ·December 6, 2020·4 min read

          Study Links Cases of ALS and FTD to a Huntington’s Disease-Associated Mutation

          Researchers find a previously unknown connection between ALS, FTD, and the Huntington's disease associated gene, huntingtin.
          Read More
          This shows neurons
          FeaturedGeneticsNeurologyOpen Neuroscience Articles
          ·July 18, 2020·5 min read

          Study Reveals Intricate Details About Huntington’s Disease Protein

          A mutated form of the huntingtin protein disrupts the normal movement of vesicles holding HT and Rab4. This leads to defects in synapses, resulting in movement abnormalities and lifespan decreases in fruit fly larvae. Findings suggest Rab4 could be a novel therapeutic target for the early intervention of Huntington's disease, before the neuronal loss and behavioral deficits associated with the neurodegenerative disorder.
          Read More
          This shows a brain slice
          FeaturedGeneticsNeurologyNeuroscience
          ·April 15, 2020·4 min read

          When damaged, the adult brain repairs itself by going back to the beginning

          Mouse models of corticospinal injuries reveal adult neurons begin a natural regeneration process by reverting back to an embryonic state. The regeneration is sustained with the help of a gene more commonly associated with Huntington's disease.
          Read More
          brain scans
          FeaturedGeneticsNeurology
          ·September 3, 2018·3 min read

          Huntington’s Disease Starts in Childhood

          Researchers say the Huntingtin gene affects brain development from an early age, even though most patients do not develop Huntington's disease until later life.
          Read More
          neurons
          FeaturedGeneticsNeurologyOpen Neuroscience Articles
          ·July 26, 2018·4 min read

          System that Could Reduce Neurodegeneration in Huntington’s Discovered

          Researchers have identified a mechanism that may reduce the toxic aggregation of the huntingtin protein. The findings could lead to new treatment options for Huntington's patients.
          Read More
          knife and fork
          FeaturedGeneticsNeurologyOpen Neuroscience Articles
          ·March 7, 2018·3 min read

          Strict Eating Schedule Can Lower Huntington’s Protein: Mouse Study

          Restricting access to food within a strict time frame stimulates autophagy and lowers levels of the huntingtin protein in the brain, a new mouse study reveals.
          Read More
          dna
          FeaturedGeneticsNeurologyOpen Neuroscience Articles
          ·February 26, 2018·3 min read

          One Step Closer to Treatment for Huntington’s

          A new study reports researchers have developed a new gene editing approach that may provide a new treatment avenue for Huntington's disease.
          Read More
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          This shows a child's head.

          Shaping Young Minds: Neurodevelopment Interventions for Psychiatric Disorders

          This shows a donut.

          Ultra-Processed Foods: AI’s New Contribution to Nutrition Science

          This shows neurons.

          Aging Myelin: A New Perspective in Alzheimer’s Disease Progression

          This shows a head and brain.

          Promising Phase 2 Trial Results for Pembrolizumab in Metastatic Brain Cancer

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