Researchers report huntingtin plays a critical role in long-term memory.
Researchers have identified a protein that can turn off the Huntingtin gene's expression.
Findings may explain how neurodegenerative diseases spread throughout the brain and disrupt normal functions. Additionally, treatment for one disease could possibly work for the other two also.
Using CRISPR gene editing to directly target RNA, researchers eliminated toxic protein buildup associated with Huntington's disease while not disrupting other human genes.
Researchers have decoded the 3D structure of the Huntingtin protein. The discovery may help develop new treatments for Huntington's disease.
UCL researchers report clinical trials of IONIS-HTTRx have shown success in reducing the huntinting protein in the nervous system of those with Huntington's disease. The drug is safe and well tolerated by human patients, the researchers note.
Researchers have developed a new way in which to measure the shape of the huntingtin protein in living cells.
A new study indicates that quickly clearing away defective proteins in the brain could help prevent some neurodegenerative disorders.
‘HD in a dish’ will facilitate search for elusive treatment. An international consortium of Huntington’s disease experts, including several from...
Researchers reveal how a repeating nucleotide sequence in the gene for a mutant protein may trigger Huntington's disease.
Researchers report Huntington's disease is not only a neurodegenerative disease, it is also a disease that affects muscle tissues.
The mutated huntingtin protein slows ribosome movement and decreases protein synthesis.
