Researchers identified specific receptors for acetylcholine that reroute information flow through memory circuits in the hippocampus. The findings could have implications for the development of drugs to help enhance or protect memory from diseases associated with cognitive decline.
Altered behaviors associated with LSD may be caused by a reduction in the normal communication between the hippocampus and visual cortex.
Amyloid-beta proteins created in the liver are carried in the blood by lipoproteins to the brain. This results in neurodegeneration, brain atrophy, and inflammation, which are common features of Alzheimer's disease.
Findings shed light on the mechanisms underlying brain damage in microgravity.
The function of the opioid system is connected to eating triggered by external stimuli. The findings could lead to the development of new therapies that target the opioid system to reduce obesity.
The habenula relays external information, such as sight and smell, along with internal states associated with emotion and learning to brain regions that govern adaptive behaviors.
Diet and exercise can influence hippocampal neurogenesis, researchers say. Poor nutrition and lack of exercise have detrimental effects on hippocampal neurogenesis, increasing the risk for dementia.
Study reaffirms findings that the gut microbiome may play a significant role in cognitive decline. Researchers found, in mice, a ketogenic diet, hypoxia, and the Bilophila wadsworthia bacteria impaired the hippocampus, leading to signs of cognitive decline.
Study identifies the role a specific protein plays in regulating the development of inhibitory synapses in the hippocampus in the context of anxiety-related behaviors.