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granule cells

·April 5, 2022·6 min read

Neurexin Controls Cerebellar Granule Cells, Offering Insight Into Autism and Schizophrenia Mechanisms

Neurexin regulates the survival of cerebellar granule cells independently of synapses. The findings shed new light on the mechanisms behind neurodevelopmental disorders like schizophrenia and ASD.

Autism Featured Neuroscience Open Neuroscience Articles

·June 4, 2019·4 min read

Exercise fine-tunes brain’s connections, eases autism spectrum disorder in mouse model

Participating in exercise improved synaptic pruning in mouse models of autism. The study also found microglia dependant synaptic pruning is impaired by maternal inflammation, which has been previously connected to the development of ASD.

Featured Neurology Neuroscience

·May 27, 2019·3 min read

Broken brain cells repaired in dementia mouse model

Chemically activating neurons and placing mice in stimulating environments reverses alterations and restores some neural connectivity in frontotemporal dementia. If translated into humans, the findings could help develop new treatments for fighting the effects of dementia in the elderly.

Featured Genetics Neuroscience Psychology

·March 12, 2019·5 min read

Scientists identify gene that keeps PTSD-like behavior at bay in female mice

A new study reveals how a prion-like protein that is encoded by the TIA1 gene helps to regulate fear memories. TIA1, researchers report, may be a promising new target for the treatment of PTSD.

Featured Neuroscience

·August 11, 2018·5 min read

An Ion Channel Differentiates Newborn and Mature Neurons in the Adult Brain

Researchers report newborn granule cells in the dentate gyrus become less excitable after three weeks. The loss of excitability is crucial for the functioning of mature neurons.

Featured Neuroscience

·June 10, 2018·4 min read

Thorny Life of New Born Neurons

A new study reports repeated stimulation enlarges dendritic spines, enabling contact with existing neural networks.

Featured Neuroscience Psychology

·December 18, 2017·6 min read

How ECT Relieves Depression: Mouse Study

John Hopkins researchers have uncovered new details that may explain, on a molecular level, how ECT relieves severe depression in mammals.

Featured Neurology Open Neuroscience Articles

·September 22, 2017·5 min read

When Neurogenesis Goes Wrong

Researchers discover post stroke neurogenesis in the hippocampus is linked to worse performance in hippocampal memory tasks.

Image shows the neural activity recorded during learning.

Electrophysiology Featured Neuroscience

·March 21, 2017·6 min read

During Learning, Neurons Deep in Brain Engage in a Surprising Level of Activity

A new study could shed light on how the cerebellum encodes information.

Featured Genetics Neuroscience

·December 26, 2016·5 min read

New Mechanism of How Brain Networks Form Identified

Inhibitory neurons form neural networks that become broader as they mature, a new study reports.

Image shows a 3d model of mossy fibers in the hippocampus.

Featured Neuroscience Open Neuroscience Articles

·November 12, 2016·4 min read

Full Detonation in the Hippocampus

Researchers report altering synaptic plasticity leads to a computational switch in a hippocampal synapse which turns the presynaptic neuron turns into “detonator” mode, causing it to fire more readily.