A new study proposes a model for how immature neurons in the dentate gyrus appear to enhance pattern separation.
Adult born granule cells appear to play a key role in memory encoding, a new study reports.
Researchers report newborn granule cells in the dentate gyrus become less excitable after three weeks. The loss of excitability is crucial for the functioning of mature neurons.
Chemically activating neurons and placing mice in stimulating environments reverses alterations and restores some neural connectivity in frontotemporal dementia. If translated into humans, the findings could help develop new treatments for fighting the effects of dementia in the elderly.
A new study could shed light on how the cerebellum encodes information.
A new study describes the epigenetic mechanisms that underlie the development of the cerebellum.
Participating in exercise improved synaptic pruning in mouse models of autism. The study also found microglia dependant synaptic pruning is impaired by maternal inflammation, which has been previously connected to the development of ASD.
Researchers report altering synaptic plasticity leads to a computational switch in a hippocampal synapse which turns the presynaptic neuron turns into “detonator” mode, causing it to fire more readily.