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Genetics

Auditory Neuroscience Featured Genetics Neuroscience

·April 27, 2025·4 min read

Tracing the Origins of Hearing

Researchers have developed a genetic "barcoding" method to trace how stem cells in embryos become neurons and inner ear cells. By labeling early stem cells in mice, the team followed their development and mapped the formation of the inner ear.

Featured Genetics Neuroscience

·April 26, 2025·3 min read

Umbilical Cord DNA May Predict Future Metabolic Health Risks

DNA changes in umbilical cord blood may help predict which children are at higher risk for future health issues like diabetes, liver disease, and stroke. Researchers analyzed chemical tags on DNA, known as methylation patterns, and linked specific alterations to markers of metabolic dysfunction later in childhood. Notably, changes in genes like TNS3, GNAS, and CSMD1 were tied to liver fat accumulation, high blood pressure, and abnormal waist-to-hip ratios.

Featured Genetics Neuroscience Psychology

·April 26, 2025·4 min read

Prenatal Stress Leaves Lasting Molecular Imprints on Babies

A new study reveals that stress during pregnancy can molecularly reprogram newborns' stress response systems, with significant differences between boys and girls. Researchers found that maternal stress altered entire families of tRNA fragments in umbilical cord blood, particularly those regulating acetylcholine, a key neurotransmitter.

Featured Genetics Neurology Neuroscience

·April 25, 2025·7 min read

AI Uncovers New Cause of Alzheimer’s

Researchers have discovered that a gene previously seen as a biomarker for Alzheimer’s disease, PHGDH, actually plays a causal role by disrupting gene regulation in the brain. Using AI, the team revealed that PHGDH has a hidden DNA-binding function unrelated to its known enzymatic activity. This malfunction triggers early Alzheimer’s development, offering a new target for prevention.

Brain Cancer Featured Genetics Neurology Neuroscience

·April 24, 2025·5 min read

Blood Test Tracks Brain Tumor Growth with Patient-Specific DNA Markers

Researchers have developed a personalized blood test that may offer a faster, less invasive way to track high-grade glioma progression. By identifying unique DNA junctions from each patient's tumor, the test can detect tumor DNA in the bloodstream, even before changes appear on MRI scans.

Featured Neuroscience

·April 24, 2025·7 min read

Maternal Childhood Trauma Linked to Rapid Weight Gain in Baby Boys

A new study reveals that maternal childhood trauma—such as neglect or abuse—can trigger rapid weight gain in male infants as early as the first two months of life. Researchers found that boys born to mothers who experienced early-life adversity gained significantly more weight per day than average, despite being full-term, healthy, and mostly breastfed.

Featured Neuroscience Psychology

·April 23, 2025·6 min read

Can Brain Scans Tell Which Antidepressant Will Work for You?

A new study shows that brain connectivity patterns, especially in the dorsal anterior cingulate cortex, can help predict how patients with major depressive disorder (MDD) will respond to antidepressants. By combining brain imaging with clinical data, researchers developed machine learning models that accurately predicted treatment outcomes across two large trials.

Featured Genetics Neurology Neuroscience Pain

·April 23, 2025·4 min read

Clearing Zombie Cells Eases Back Pain

A new preclinical study has found that two drugs—o-Vanillin and RG-7112—can clear “zombie cells” from spinal discs, potentially treating the root cause of chronic low back pain. These senescent cells accumulate with age or injury and cause inflammation, pain, and tissue damage.

Brain Cancer Featured Genetics Neurology Neuroscience

·April 22, 2025·6 min read

Spatial Gene Hubs Reveal Hidden Drivers of Brain Cancer

A new study reveals that the way DNA folds inside brain cells plays a critical role in glioblastoma, one of the deadliest forms of brain cancer. Researchers discovered that in cancer cells, genes cluster into 3D "hubs" that coordinate tumor-driving activity, even without mutations.

Featured Neuroscience Psychology Visual Neuroscience

·April 22, 2025·4 min read

Eye Clues to Schizophrenia Risk Found in Retinal Thickness

The retina, as part of the central nervous system, may reflect early signs of brain disorders like schizophrenia. A large-scale genetic study found that people with higher genetic risk for schizophrenia tend to have thinner retinas, even in the absence of symptoms.

Featured Genetics Neurology Neuroscience

·April 22, 2025·5 min read

Microglia Reprogrammed to Deliver Precision Alzheimer’s Therapies

Researchers have developed engineered human microglia that detect disease-related brain changes and release therapeutic proteins precisely where needed. Using CRISPR technology, the team programmed these cells to secrete an enzyme that breaks down beta-amyloid plaques only in affected areas.

Featured Neurology Neuroscience

·April 21, 2025·6 min read

Early Alzheimer’s Clues Found in Adults as Young as 24

A new study reveals that cognitive changes tied to Alzheimer's risk factors begin far earlier in life than previously thought, some as early as age 24. Researchers found associations between memory performance and cardiovascular risk factors, immune markers, and Alzheimer’s biomarkers (amyloid, tau, and neurodegeneration) in individuals aged 24–44.

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