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Genetics

Featured Genetics Neurology Neuroscience Open Neuroscience Articles

·June 27, 2019·3 min read

Dementia study links gene with damage to brain connections

Post mortem examinations of brain tissue from Alzheimer's patients revealed synapses contained clumps of clusterin, in addition to amyloid beta. The clumps were more abundant in those with genetic risk factors from Alzheimer's disease.

Featured Genetics Neuroscience Open Neuroscience Articles Psychology

·June 26, 2019·4 min read

Boosting amino acid derivative may be a treatment for schizophrenia

Reduced levels of an amino acid called betaine is associated with schizophrenia pathology. Supplementing betaine levels improved cognitive and behavioral deficits in mouse models of schizophrenia. The amino acid also reduced oxidative stress at the molecular level.

This diagram shows how a-synuclein travels from the gut to the brain via the vagus nerve

Featured Neurology Neuroscience Neuroscience Videos Open Neuroscience Articles

·June 26, 2019·6 min read

New research shows Parkinson’s disease origins in the gut

A new study adds to the growing body of evidence that Parkinson's disease may start in the gut. Researchers found gut-to-brain propagation of alpha-synuclein spread via the vagus nerve. The study provides a more accurate model of Parkinson's progression and could lead to new treatments to halt or prevent this neurodegenerative disease.

This shows a person with pills in their hand

Featured Neurology Neuroscience Open Neuroscience Articles Psychology

·June 25, 2019·4 min read

Common antidepressants interact with opioid med to lessen pain relief

SSRI antidepressants, such as Prozac and Paxil, interact with opioid medications to make them less effective at providing relief from chronic pain. Tramadol relies on activation of the CYP2D6 enzyme to control pain, but SSRIs inhibit this enzyme. Researchers suggest prescribing different classes of antidepressants which do not suppress the enzyme may benefit those in need of opioid medications. Alternatively, non-opioid pain killers should be considered for those who can not switch from SSRIs.

Featured Genetics Neurology Neuroscience Open Neuroscience Articles Psychology

·June 25, 2019·4 min read

Mechanisms underlying early life stress and irritable bowel syndrome discovered

Mice that experienced early life stress and later developed irritable bowel syndrome had significantly higher levels of intestinal stem cells and enterochromaffin (EC). Additionally, the mice expressed elevated secretion of serotonin as a result of the increased EC cell density.

This shows macrophages in GBM tissue samples

Brain Cancer Featured Neurology Neuroscience

·June 25, 2019·4 min read

Scientists track brain tumor turncoats with advanced imaging

Advanced imaging techniques visualize macrophages in brain tumors in mouse models of glioblastoma.

This shows amyloid beta, tau and microglia

Featured Genetics Neurology Neuroscience

·June 24, 2019·4 min read

Alzheimer’s missing link ID’d, answering what tips brain’s decline

Study in mice and humans reveals reinforcing the activity of microglia could slow, or potentially halt, the proliferation of Tau tangles in Alzheimer's disease.

Featured Genetics Neurology Neuroscience

·June 24, 2019·2 min read

Alzheimer’s disease: Sex affects tau accumulation in the brain

Women with the ApoE e4 genetic risk factor for Alzheimer's are more susceptible to tau accumulation in the brain than men.

Featured Neuroscience

·June 24, 2019·2 min read

Researchers identify new hunger pathway in the brain

Newly identified network in the hypothalamus alters feeding behaviors on a shorter timescale. The pathway affects food intake and body weight by releasing GABA, which may occur due to the detection, and not the consumption of food.

Featured Genetics Neuroscience

·June 21, 2019·3 min read

Discovery of the cell fate switch from neurons to astrocytes in the developing brain

The FGF signaling pathway is an important extracellular regulator in the fate of neural stem cells switching from neurons to astrocytes in the cerebral cortex.

Featured Neurology Neuroscience

·June 20, 2019·5 min read

Fibromyalgia linked to variations in microbiome composition

Using a range of clinical techniques, including deep learning, researcher identify changes in the microbiome of people with fibromyalgia which were not associated with diet, medications or aging. Additionally, the severity of symptoms was directly correlated with an increased presence, or more pronounced absence, of certain bacterias.

Featured Genetics Neurology Neuroscience Open Neuroscience Articles

·June 20, 2019·5 min read

Epilepsy and sudden death linked to bad gene

Mice expressing a specific variant of the Scn1a gene associated with Dravet syndrome exhibited spontaneous seizures, disordered breathing and died prematurely.

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Genetics

Dementia study links gene with damage to brain connections

Boosting amino acid derivative may be a treatment for schizophrenia

New research shows Parkinson’s disease origins in the gut

Common antidepressants interact with opioid med to lessen pain relief

Mechanisms underlying early life stress and irritable bowel syndrome discovered

Scientists track brain tumor turncoats with advanced imaging

Alzheimer’s missing link ID’d, answering what tips brain’s decline

Alzheimer’s disease: Sex affects tau accumulation in the brain

Researchers identify new hunger pathway in the brain

Discovery of the cell fate switch from neurons to astrocytes in the developing brain

Fibromyalgia linked to variations in microbiome composition

Epilepsy and sudden death linked to bad gene

Hearing Aids Linked to 23% Lower Dementia Risk in Epilepsy

Reading Is the Ultimate Cognitive Enhancer

Dual Brain-Machine Interfaces Unlock Bionic Hand Kinesthesia

Overcoming Endothelial Sorting to Cure Glioblastoma

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