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Genetics

·April 12, 2025·4 min read

Newly Discovered Gene Mutation Linked to Neurodevelopmental Disorders

Researchers have identified mutations in the non-coding gene RNU2-2 as a cause of a newly defined neurodevelopmental disorder, often accompanied by severe epilepsy. The discovery sheds light on the critical role of small non-coding genes in brain development and could affect thousands of families globally.

Autism Featured Neuroscience Psychology

·April 12, 2025·4 min read

Puberty Brain Shift May Explain Autism in Genetic Disorder

Summary: Researchers have identified changes in brain connectivity before and after puberty that may explain why some children with chromosome...

Featured Genetics Neuroscience

·April 12, 2025·5 min read

Brain Enzyme Limits Risk of Drug Relapse

New research reveals that the enzyme HDAC5 plays a critical role in suppressing a gene (Scn4b) that regulates brain activity associated with drug-related memories, which are central to relapse in substance use disorders (SUDs). By limiting expression of Scn4b, HDAC5 reduces the excitability of neurons in the brain’s reward system, weakening the formation of powerful drug-environment associations.

Featured Genetics Neuroscience

·April 12, 2025·5 min read

New Genes Linked to Parkinson’s Risk Revealed

Researchers have long wondered why some people with high-risk Parkinson’s gene variants develop the disease while others don’t. A new study has uncovered that additional genetic players, particularly the Commander gene complex, influence whether the disease manifests.

Auditory Neuroscience Featured Genetics Neuroscience

·April 12, 2025·4 min read

Six1 Protein May Unlock New Clues to Congenital Hearing Loss

Congenital deafness affects roughly one in 1,000 babies and is often linked to genetic mutations, many of which remain unidentified. Researchers have now pinpointed a new set of candidate genes regulated by the protein Six1, which plays a critical role in inner ear development.

Featured Genetics Neurology Neuroscience

·April 11, 2025·6 min read

Hidden Neural Stem Cells May Hold Key to Brain Regeneration

Scientists have identified a previously unknown type of neural stem cell (pNSC) that exists outside the brain and spinal cord, overturning decades of neuroscience dogma. These peripheral neural stem cells, discovered in tissues like the lung and tail of mice, share key properties with brain-derived neural stem cells, including the ability to self-renew and differentiate into neurons.

Featured Genetics Neurology Neuroscience

·April 10, 2025·5 min read

Blocking Tim-3 Boosts Microglia in Alzheimer’s

New research reveals that the immune checkpoint molecule Tim-3 plays a critical role in how microglia, the brain’s immune cells, respond to Alzheimer’s disease. While Tim-3 normally helps maintain brain homeostasis, it can also inhibit microglia from clearing harmful plaques that accumulate in Alzheimer’s.

Featured Genetics Neurology Neuroscience

·April 10, 2025·3 min read

Mini-Brain Models Reveal a New Dementia-Linked Protein Pathway

Scientists have discovered a new protein pathway involved in neurodegeneration by studying “mini-brain” organoids made from patients with frontotemporal lobar degeneration (FTLD). They found that the protein GRAMD1B plays a crucial role in managing cholesterol and lipid balance within neurons—processes closely linked to Alzheimer’s and FTLD.

Featured Neurology Neuroscience

·April 9, 2025·2 min read

Dad’s Alzheimer’s May Raise Tau Levels in Your Brain

New research reveals that people with a father who had Alzheimer’s may be more vulnerable to the spread of tau protein in the brain, a hallmark of the disease. The study followed 243 individuals with a family history of Alzheimer’s over nearly seven years and found that those with affected fathers, especially women, showed greater tau buildup.

Autism Featured Genetics Neuroscience

·April 4, 2025·4 min read

Autism-Linked Gene Alters Face Perception in Dogs

A new study shows that Beagle dogs with mutations in the autism-linked Shank3 gene exhibit face processing abnormalities similar to those seen in humans with ASD. Using behavioral tests, eye-tracking, and brain recordings, researchers found that these dogs paid less attention to faces—especially the eye region—and showed delays in brain responses to facial cues.

Autism Featured Genetics Neuroscience

·April 3, 2025·6 min read

MicroRNAs Guide Purkinje Cell Growth, Shedding Light on Autism Links

A new study reveals that microRNAs—tiny regulators of gene expression—play a crucial role in shaping Purkinje cells, rare brain neurons linked to movement and neurodevelopmental disorders. Using advanced genetic tools, researchers showed that disabling microRNAs during specific developmental windows impaired the cells’ growth and ability to form key connections.

Autism Featured Genetics Neuroscience Open Neuroscience Articles

·April 1, 2025·4 min read

Protein Imbalance Triggers Autism-Like Behavior

A new study reveals that autism-like symptoms in mice emerge when two nerve proteins—MDGA2 and BDNF—fall out of balance. MDGA2 typically keeps BDNF/TrkB signaling in check, but when MDGA2 levels drop, heightened neuronal activity and social impairments occur.

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Genetics

Newly Discovered Gene Mutation Linked to Neurodevelopmental Disorders

Puberty Brain Shift May Explain Autism in Genetic Disorder

Brain Enzyme Limits Risk of Drug Relapse

New Genes Linked to Parkinson’s Risk Revealed

Six1 Protein May Unlock New Clues to Congenital Hearing Loss

Hidden Neural Stem Cells May Hold Key to Brain Regeneration

Blocking Tim-3 Boosts Microglia in Alzheimer’s

Mini-Brain Models Reveal a New Dementia-Linked Protein Pathway

Dad’s Alzheimer’s May Raise Tau Levels in Your Brain

Autism-Linked Gene Alters Face Perception in Dogs

MicroRNAs Guide Purkinje Cell Growth, Shedding Light on Autism Links

Protein Imbalance Triggers Autism-Like Behavior

When Obsession Masquerades as Love: Understanding Limerence

How Psychology Has Shaped, and Continues to Shape, AI

Why You Sometimes Don’t Feel Pain Until It’s Too Late

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