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gene therapy

Featured Genetics Neurology Open Neuroscience Articles

·March 19, 2021·3 min read

Gene Therapy Using ‘Zinc Fingers’ May Help Treat Alzheimer’s Disease

A new genetic engineering strategy significantly reduces levels of tau in animal models of Alzheimer's disease. The treatment, which involves a single injection, appears to have long-last effects.

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Featured Genetics Neurology

·February 19, 2021·4 min read

First-in-Human Clinical Trial to Assess Gene Therapy for Alzheimer’s Disease

Researchers launch the first-in-human phase 1 clinical trial to assess the safety and efficacy of a gene therapy which will deliver BDNF to the brains of those with Alzheimer's and mild cognitive impairment.

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Brain Cancer Featured Genetics Open Neuroscience Articles

·August 17, 2020·2 min read

Gene Targeting Helps Overcome the Resistance of Brain Cancer to Therapy

Mouse study reveals the deletion of the OSMR gene significantly improves glioblastoma tumor response to therapy and extended lifespan.

Featured Neurology Neuroscience Videos

·July 30, 2020·4 min read

New Hope as Dementia Therapy Reverses Memory Loss

Activating p38gamma, a naturally protective enzyme in the brain, may help to prevent the development of Alzheimer's disease symptoms. Researchers showed the naturally protective effects of p38gamma could be harnessed to improve memory in the later stages of Alzheimer's disease.

Featured Genetics Neurology

·July 29, 2020·6 min read

Getting Gene Therapy to the Brain

Researchers successfully applied a gene therapy platform to completely correct brain defects in a large animal model of a human genetic disease.

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Featured Genetics Neuroscience Open Neuroscience Articles Visual Neuroscience

·May 1, 2020·5 min read

New gene therapy for complete color blindness tested in patients

New gene therapy may help those with achromatopsia, or complete color blindness, to improve visual function. The treatment targets the CNGA3 gene, which is implicated in one-third of achromatopsia cases.

Featured Genetics Neurology Neuroscience Open Neuroscience Articles

·January 3, 2020·2 min read

Using gene therapy to treat CTE

A newly developed adeno-associated virus vector can deliver an anti-p Tau antibody directly to the hippocampus, significantly reducing pTau levels associated with CTE.

This shows the retina with and without gene therapy

Featured Genetics Neuroscience Visual Neuroscience

·July 8, 2019·3 min read

Retina restructures itself after cell death

Gene therapy can restore the structure of the retina and regain normal light responses.

This shows baby Arabella Smygov following gene therapy treatment for SMA

Featured Genetics Neurology Neuroscience

·June 10, 2019·7 min read

‘Like Looking at a Miracle’: Baby Blossoms Thanks to Gene Therapy For Spinal Muscular Atrophy

Zolgensma, an FDA approved gene therapy, supplements the production of the SMN protein to improve motor neuron function in children with spinal muscular atrophy after just one dose.