Latest

gene therapy

Auditory Neuroscience Featured Genetics Neuroscience

·August 11, 2023·4 min read

Hearing Loss Reversed Using Gene Therapy

Researchers made a breakthrough in reversing hearing loss in mice. By targeting the inactive Spns2 gene and activating it using a specific enzyme, the team successfully restored the mice's hearing in low and middle frequency ranges.

Featured Genetics Neuroscience

·July 3, 2023·6 min read

AI Predicts CRISPR’s RNA-Targeting Effects, Revolutionizing Gene Therapy

Researchers developed a deep learning model, TIGER, that accurately predicts on- and off-target activity of RNA-targeting CRISPR tools. This new approach allows the fine-tuning of gene activity in human cells.

Featured Genetics Neuroscience Visual Neuroscience

·April 26, 2023·3 min read

Gene Therapy for Dogs With Inherited Blinding Eye Disease Set for Human Trials

A groundbreaking gene therapy proven successful in treating an inherited, blinding eye disease in dogs is now poised for clinical trials in humans with the rare condition retinitis pigmentosa. The therapy, which halts vision loss by introducing a normal copy of the CNGB1 gene, could potentially benefit around 2 million people affected worldwide.

Featured Genetics Neurology Neuroscience

·November 22, 2022·4 min read

Gene-Delivering Viruses Reach the Brain in Step Toward Gene Therapy for Neurological Diseases

Researchers have developed a family of adeno-associated viral vectors (AAVs) that are able to cross the blood-brain barrier to deliver gene therapies directly to the brain.

Featured Neuroscience

·October 21, 2022·5 min read

Using Light Stimulation to Modulate Brain Waves

Researchers have developed a new system that comprises of a brain implant containing LEDs and gene therapy to modulate brain waves. The technology showed success in suppressing abnormal brain waves akin to those seen during an epileptic seizure.

Featured Genetics Neuroscience Open Neuroscience Articles Visual Neuroscience

·October 10, 2022·4 min read

Gene Therapy Rapidly Improves Night Vision in Adults With Congenital Blindness

Gene therapy enables a striking recovery of night vision in those who suffer from the childhood-onset blindness disorder Leber Congenital Amaurosis.

Featured Genetics Neuroscience Visual Neuroscience

·August 25, 2022·3 min read

New Gene Therapy Shows Promise for Treating Age Related Macular Degeneration

A new study reports that a new gene therapy shows promise in treating dry age-related macular degeneration. The gene therapy, ophNdi1, directly targets mitochondrial function that is malfunctioning in AMD.

Featured Genetics Neuroscience Visual Neuroscience

·August 23, 2022·4 min read

Gene Therapy for Completely Color Blind Children Partly Restores Cone Function

Researchers partially restored the function of cone receptors in the retinas of children born completely blind by using gene therapy.

Featured Genetics Neurology Neuroscience

·May 9, 2022·4 min read

Gene Therapy Shows Promise in Treating Neuropathy From Spinal Cord Injuries

Gene therapy that inhibits targeted nerve cell signals effectively improves symptoms of neuropathic pain without negative side effects in mouse models of spinal cord injury or peripheral nerve damage.

Autism Featured Genetics Neuroscience Open Neuroscience Articles

·May 2, 2022·5 min read

Gene Therapy Reverses Effects of Autism-Linked Mutation in Brain Organoids

A brain organoid study reveals how a genetic mutation associated with Pitt-Hopkins syndrome, a profound form of autism, disrupts neural development. Using gene-editing technology, researchers recovered the function of the TCF4 gene and effectively restored neural structure and function.