Brain CancerFeaturedNeurologyNeuroscienceOpen Neuroscience Articles·May 30, 2019·4 min readPairing of glutamine-targeting drug and ketogenic diet fights glioblastoma in miceCombining an antibiotic drug that targets glutamine with the ketogenic diet helps kill glioblastoma cancer cells, reversing symptoms of the disease and improving survivability in mouse models.Read More
Brain CancerFeaturedGeneticsNeuroscienceOpen Neuroscience Articles·April 16, 2019·4 min readScientists ‘reverse engineer’ brain cancer cells to find new targets for treatmentUsing CRISPR-Cas9 gene editing, researchers identified actionable pathways responsible for the growth of glioblastoma stem cells. By reverse engineering brain cancer cells, multiple potential new targets for cancer treatments have been uncovered.Read More
Brain CancerFeaturedNeurologyNeuroscience·March 31, 2019·4 min readNew glioblastoma vaccine shows promising results in phase Ib clinical trialA new vaccine for glioblastoma brain cancer suspends tumor growth and is well tolerated by patients, according to the results of an early phase clinical trial.Read More
Brain CancerFeaturedGeneticsNeurologyNeuroscience·February 11, 2019·5 min readImmunotherapy Can Be Effective in Treating People with Recurrent GlioblastomaResearchers report administering immunotherapy treatment prior to surgery for those with recurring glioblastoma brain cancer is more effective that using the treatment after surgery.Read More
Brain CancerFeaturedGeneticsNeurologyNeuroscienceOpen Neuroscience Articles·January 25, 2019·4 min readThe Hitchhiker’s Guide to Defeating GlioblastomaResearchers have developed a new approach that uses microRNA in combination with chemotherapy to help treat glioblastoma brain cancer. In preclinical models, the approach increases survival of the deadly brain cancer five fold.Read More
Brain CancerFeaturedGeneticsNeurologyNeuroscience·January 11, 2019·6 min readA Patient’s Sex Matters When it Comes to Brain CancerResearchers report our gender can determine longevity and response to treatment for glioblastoma brain cancer. The study reports male survival is determined by genes that control cell division, where as female survival is often determine by genes that regulate the ability of cancer cells to migrate to different brain areas.Read More
Brain CancerFeaturedGeneticsNeurologyOpen Neuroscience Articles·January 2, 2019·7 min readSex Differences Identified in Glioblastoma Brain CancerA new study reveals distinct molecular differences in signatures of glioblastoma brain cancer between men and women. Researchers report current treatments for the brain cancer are more effective in women than in men. The findings could help to tailor treatments aimed at the different sexes and improve survival.Read More
Brain CancerFeaturedNeurologyOpen Neuroscience Articles·November 19, 2018·3 min readDrug Discovery Could Halt Brain Cancer SpreadResearchers detail the use of a drug that may help block the way glioblastoma brain cancer cells respond to fluid flow. The finding could lead to stopping glioblastoma from spreading.Read More
Brain CancerFeaturedGeneticsNeurology·June 6, 2018·4 min readBrain Cancer Atlas CreatedA new brain cancer atlas maps out comprehensive, visually rich information about the anatomical and genetic bases of glioblastoma, researchers report.Read More
Brain CancerFeaturedGeneticsNeurology·June 4, 2018·5 min readA Potential Achilles Heel in Brain CancerA new study in PNAS reports blocking the expression of MDA-9/Syntenin forces glioma stem cells to lose their ability to induce protective autophagy.Read More
Brain CancerFeaturedNeurologyOpen Neuroscience Articles·May 24, 2018·5 min readTiny Particles Could Help Fight Brain CancerResearchers at MIT have developed a new drug delivering nanoparticle that is able to cross the blood-brain barrier. The nanoparticles carry two different drugs that can help shrink tumors and prevent them from growing back.Read More
Brain CancerFeaturedGeneticsNeurologyOpen Neuroscience Articles·April 25, 2018·4 min readOrganoids Reveal how Deadly Brain Cancers GrowResearchers use gene editing to generate aggressive glioblastoma multiforme brain tumors in the lab. The model, researchers say, could be used to track the progression of tumors and develop personalized therapies for patients.Read More