Brain cancer cells resist therapy by temporarily losing gene mutations targeted by drugs, but re-amplify the mutation once the treatments have stopped, a new study reports. Read More
A novel therapeutic, which is based on nanotechnology, turns off a critical gene and increases survival rates in mice with glioblastoma brain cancer, a new study reports. Read More
Researchers delve deeply into the genomics of 599 GBM brain cancer cases to better target the disease. Read More
A new drug could help increase the effectiveness of radiation therapy for patients with glioblastoma multiforme, the most deadly form of brain cancer. The ATM kinase inhibitor, in combination with radiation therapy, helped significantly extend survival rates in mouse models of GBM. Read More
“We identified a subset of brain tumor cells that are slower growing or remain at rest, and appear to be the source of cancer recurrence after standard therapy in which the drug temozolomide is given to stop the tumor’s growth,” said Dr. Luis Parada. “Current therapy targets fast-growing tumor cells but not those responsible for new tumors. To the best of our knowledge, this is the first identification of a cancer stem-like cell in a spontaneously forming tumor inside a mammal.” Read More
New research from the University of Wisconsin-Madison explains why the incurable brain cancer, glioblastoma multiforme (GBM), is highly resistant to... Read More
