In mice, the failed epigenetic suppression of Xist leads to fetal developmental abnormalities and miscarriage. Knocking out the Xist gene greatly reduced prenatal death. The findings have implications for understanding infertility and developing new treatments to prevent miscarriage.
Your epigenetic "age" can predict your risk of developing cognitive impairments and dementia later in life, a new study reports. Epigenetic age takes into account specific personal epigenetic changes that occur in relation to your biological age.
Teens who experience maladaptive relationships show physical and epigenetic signs of premature aging when they reach adulthood.
Researchers have developed a new imaging approach that captures DNA methylation in the brain.
H3 acetylation of basal neural precursor cells may have been an important factor in the evolution of the human neocortex.
Combining two natural products that modulate the epigenome, researchers believe they have identified a feasible approach to reversing symptoms of PTSD in animal models that could be effective in humans.
Growing up and experiencing stimulating environments throughout life help to keep the hippocampus "young", and can help to preserve mental fitness in old age.
A new study sheds light on how genes are regulated in dementia. Researchers also identified 84 novel genes linked to dementia.
Stressed male mice can pass down their behaviors to their offspring via alterations in their sperm's DNA, a new study reports.
A new study of male guppies reveals behaviors affected by methylphenidate hydrochloride (MPH), an active ingredient in common ADHD medications, can be passed along to future generations.
Regulatory epigenetic changes to genomic regions in the brain are essential for human cognition and mental health.
Researchers explore the link between childhood trauma and the increased risk of developing mental and physical health problems as adults.