Infant children whose mothers experienced neglect when they were young showed altered brain circuitry in areas associated with anxiety and fear response. Read More
Researchers used epigenetic modulators to reduce the damage done by stress to neuroplasticity. Findings reveal acute intervention in epigenetic mechanisms produced antidepressant effects more rapidly than conventional medications. Read More
Focusing on gene changes as a result of epigenetic processes, such as aging, researchers were able to reverse elevated levels of harmful genes associated with memory deficits in Alzheimer's disease. Read More
Stress in women either before or during pregnancy can increase the risk of preterm birth and accelerate aging in their offspring. Read More
PBDEs, common flame retardants found on household furniture, caused an increased risk of diabetes in mice only exposed to the chemicals through their mother's milk. In addition to increased glucose intolerance, researchers also noted higher levels of endocannabinoid in the livers of the offspring of mice exposed to PBDEs. Read More
Using brain tissue samples, researchers have identified a new epigenetic clock for brain aging. The study reveals how the epigenetic clock could provide insight into accelerated brain aging and neurodegenerative disorders. Read More
Early childhood trauma has an impact on glucose metabolism and blood composition, which are passed on to the next generation. Read More
Researchers conduct the first study to use nonharmful stress, like intermittent systemic hypoxia, to protect against disease in the first generation offspring in mice. Read More
Twin study reveals how we adapt to aging may be genetically influenced. Individual differences in blood DNA methylation are partly heritable later in life and longitudinally across a decade, researchers report. Read More
Mouse study reveals the sperm of males infected with Toxoplasma carries an altered epigenetic signature that impacts the brain of the offspring. While the effects of T. gondii infections in pregnant women are fairly well documented, this is a novel study looking at the impact of male infection and its impact on offspring. The study raises the question as to whether T. gondii infections in men before conception impact the health and development of future generations. Read More
Key biomarkers for predicting autism in newborns have been identified. Read More
Cortical and subcortical memory regions exhibit distinct genetic signatures that reflect potential differences in health and disease. Read More
