Twins who were more physically active had lower signs of metabolic disease and epigenetic markers linked to decreased risk of metabolic syndrome. Findings suggest metabolic diseases are strongly influenced by how a person interacts with their environment as opposed to just their inherited genetics.
The epigenetic clocks of those who indulged in unhealthy behaviors as teens were 1.7 to 3.3 years older than individuals who reported more healthy lifestyles as teens.
Post-mortem analysis of the brains of those with Parkinson's disease revealed more than 200 genes with different epigenetic markers compared to healthy brains, but the affected genes were almost entirely different between women and men.
Obesity is, in part, determined by epigenetic development in the arcuate nucleus of the hypothalamus. Findings suggest developmental epigenetics plays a significant role in both environmental and genetic influences on obesity risk.
By altering the epigenetic markers on chromosomes, researchers witnessed changed gene expression in offspring and grand-offspring. The findings reveal the occurrence of transgenerational epigenetic inheritance.
Epigenetic traces of childhood trauma can be used as biomarkers to predict the risk of addiction, depression, and a range of other physical and mental health issues 17 years later.
Members of the British military who witnessed nuclear test programs in the 1950s and 60s are no more likely to pass on genetic alterations to their offspring and future generations than other members of the military, a new study reports.
Common epigenetic markers associated with food addiction have been identified.
In mice, the failed epigenetic suppression of Xist leads to fetal developmental abnormalities and miscarriage. Knocking out the Xist gene greatly reduced prenatal death. The findings have implications for understanding infertility and developing new treatments to prevent miscarriage.
Your epigenetic "age" can predict your risk of developing cognitive impairments and dementia later in life, a new study reports. Epigenetic age takes into account specific personal epigenetic changes that occur in relation to your biological age.