Researchers used epigenetic modulators to reduce the damage done by stress to neuroplasticity. Findings reveal acute intervention in epigenetic mechanisms produced antidepressant effects more rapidly than conventional medications.
A new study of male guppies reveals behaviors affected by methylphenidate hydrochloride (MPH), an active ingredient in common ADHD medications, can be passed along to future generations.
Teenage binge drinking is linked to altered gene expression in the brain, specifically the central nucleus of the amygdala. Adolescent rats exposed to alcohol had increased levels of miR-137, resulting in lower expression of proteins essential for healthy neuron growth. During adulthood, these rats displayed higher levels of anxiety and an increased preference for alcohol consumption.
Researchers have released data from the world's largest brain and body scanning study.
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Researchers have identified the first gene mutation associated with a chronic and often fatal form of neuroblastoma that typically strikes...
Donepezil, a drug routinely administered to slow cognitive decline in Alzheimer's disease, shows promise in treating damage caused to the brain by adolescent alcohol exposure. The drug reverses neuroinflammation and neuron damage in rats exposed to alcohol during adolescence.
In mice, the failed epigenetic suppression of Xist leads to fetal developmental abnormalities and miscarriage. Knocking out the Xist gene greatly reduced prenatal death. The findings have implications for understanding infertility and developing new treatments to prevent miscarriage.