Regulatory epigenetic changes to genomic regions in the brain are essential for human cognition and mental health. Read More
Researchers explore the link between childhood trauma and the increased risk of developing mental and physical health problems as adults. Read More
Immune cells in the uterus and placenta of stressed pregnant mice were not activated, but researchers found increased levels of inflammation in the developing fetal brain. Additionally, prenatal stress led to reductions in gut microbial strains and functions, especially in those linked to inflammation. Read More
Early life stress induces epigenetic modifications in D2-type medium spiny neurons in the nucleus accumbens, increasing the susceptibility to stress in adulthood. Read More
From impairing nervous system function and changing bacterial communities in the microbiome to increasing oxidative stress and inflammation, researchers report on the ways in which exposure to chemical pollution harms the body. Read More
Stress experienced by fathers during early life was associated with more rapid development of white matter tracts in his child's brain. Read More
Infant children whose mothers experienced neglect when they were young showed altered brain circuitry in areas associated with anxiety and fear response. Read More
Researchers used epigenetic modulators to reduce the damage done by stress to neuroplasticity. Findings reveal acute intervention in epigenetic mechanisms produced antidepressant effects more rapidly than conventional medications. Read More
Focusing on gene changes as a result of epigenetic processes, such as aging, researchers were able to reverse elevated levels of harmful genes associated with memory deficits in Alzheimer's disease. Read More
Stress in women either before or during pregnancy can increase the risk of preterm birth and accelerate aging in their offspring. Read More
PBDEs, common flame retardants found on household furniture, caused an increased risk of diabetes in mice only exposed to the chemicals through their mother's milk. In addition to increased glucose intolerance, researchers also noted higher levels of endocannabinoid in the livers of the offspring of mice exposed to PBDEs. Read More
Using brain tissue samples, researchers have identified a new epigenetic clock for brain aging. The study reveals how the epigenetic clock could provide insight into accelerated brain aging and neurodegenerative disorders. Read More
