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endoplasmic reticulum

Featured Neuroscience

·September 26, 2022·4 min read

The Neural Cartography of Smell

The experience of every odor derives from precise circuitry in the brain.

Autism Featured Neuroscience Open Neuroscience Articles

·July 19, 2022·3 min read

Autism-Related Mutations Inhibit Export of Key Protein From Endoplasmic Reticulum

Study finds an autism-related genetic mutation increases splicing errors and induces endoplasmic reticulum stress by activating the unfolded protein response.

Featured Neurology Neuroscience Open Neuroscience Articles

·May 6, 2022·4 min read

‘Stressed’ Cells Offer Clues to Eliminating Build-up of Toxic Proteins in Dementia

Study reveals a new mechanism that appears to reverse the build-up of protein aggregates by refolding them, rather than removing them.

This shows a brain in a lightbulb and an alarm clock

Featured Neuroscience Open Neuroscience Articles

·March 23, 2022·3 min read

Mechanism for Long-Term Memory Storage Identified

A novel protein folding mechanism in the endoplasmic reticulum is essential for long-term memory storage. This mechanism is impaired in tau-models of Alzheimer's disease, but restoring the protein folding mechanism reverses memory impairment associated with dementia.

Brain Cancer Featured Neurology Neuroscience

·December 23, 2020·4 min read

Anti-Diarrhea Drug Drives Cancer Cells to Cell Death

Loperamide, an anti-diarrhea medication, induces autophagy in glioblastoma brain cancer cells.

This is a drawing from a Sleeping Beauty book

Featured Genetics Neuroscience

·January 15, 2020·3 min read

Beauty sleep could be real, say body clock biologists

Study shows how circadian clock mechanisms boost our ability to maintain our bodies when we are most active.

Featured Neuroscience Neuroscience Videos

·February 7, 2019·5 min read

This Is a Neuron on Nicotine

Researchers have developed a protein sensor which allows for the observation of nicotine's movement in cells.

Featured Neuroscience Open Neuroscience Articles

·November 15, 2018·4 min read

Seeing and Smelling Food Prepares the Liver for Digestion: Mouse Study

Researchers say the sight and smell of food alone may be enough to prompt the liver to start the processes that help digest food.

Featured Genetics Neuroscience

·April 19, 2018·4 min read

Neurons Derived From Super-Obese People Respond Differently to Appetite Hormone

According to researchers, neurons generated from super obese people are more likely to dysregulate hormones related to hunger and feeding behaviors.

Featured Genetics Neurology Open Neuroscience Articles

·October 17, 2017·4 min read

Resolving Traffic Jams in Human ALS Motor Neurons

Researchers have generated motor neurons from people with familial ALS who carry FUS mutations.

Image shows a diagram of the endoplasmic reticulum.

Featured Genetics Neurology Open Neuroscience Articles

·April 24, 2017·4 min read

A Step Closer to Unraveling Mystery Cause of Multiple Sclerosis

Researchers have discovered a new cellular mechanism that may be a root cause of multiple sclerosis.

Featured Neurology Open Neuroscience Articles

·March 23, 2017·4 min read

Possible New Treatment for Multiple Sclerosis

Researchers identify a new cellular mechanism that may be responsible for multiple sclerosis. Findings could open up new avenues for the development of treatments.