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endoplasmic reticulum

Featured Neurology Neuroscience Open Neuroscience Articles

·May 6, 2022·4 min read

‘Stressed’ Cells Offer Clues to Eliminating Build-up of Toxic Proteins in Dementia

Study reveals a new mechanism that appears to reverse the build-up of protein aggregates by refolding them, rather than removing them.

Image shows a diagram of the endoplasmic reticulum.

Featured Genetics Neurology Open Neuroscience Articles

·April 24, 2017·4 min read

A Step Closer to Unraveling Mystery Cause of Multiple Sclerosis

Researchers have discovered a new cellular mechanism that may be a root cause of multiple sclerosis.

Brain Cancer Featured Neurology Neuroscience

·December 23, 2020·4 min read

Anti-Diarrhea Drug Drives Cancer Cells to Cell Death

Loperamide, an anti-diarrhea medication, induces autophagy in glioblastoma brain cancer cells.

Autism Featured Neuroscience Open Neuroscience Articles

·July 19, 2022·3 min read

Autism-Related Mutations Inhibit Export of Key Protein From Endoplasmic Reticulum

Study finds an autism-related genetic mutation increases splicing errors and induces endoplasmic reticulum stress by activating the unfolded protein response.

This is a drawing from a Sleeping Beauty book

Featured Genetics Neuroscience

·January 15, 2020·3 min read

Beauty sleep could be real, say body clock biologists

Study shows how circadian clock mechanisms boost our ability to maintain our bodies when we are most active.

The image shows the nucleus of a cell in blue. It is adjacent to the rough endoplasmic reticulum in green.

Featured Genetics

·September 11, 2014·3 min read

Cells Put off Protein Production During Times of Stress

A new study could provide additional insights into neurodegenerative diseases which result from misfolded proteins piling up.

Diagram explains how PERK can cause cell death in parkinson's.

Featured Genetics Neurology

·June 23, 2016·4 min read

Challenging Current Views on Origins of Parkinson’s

A new study reports stress on the endoplasmic reticulum, and not mitochondrial failure, results in neurodegeneration in Parkinson's disease.

Image shows a schematic for MAM distribution in ALS.

Featured Genetics Neurology Open Neuroscience Articles

·November 8, 2016·3 min read

Collapse of Mitochondria-Associated Membrane in ALS

Researchers report a collapse of the mitochondria-associated membrane is a common halmark in two genetic forms of ALS.

Image shows stem cells asymmetrically segregate damaged proteins.

Featured Genetics Neuroscience

·September 17, 2015·3 min read

Diffusion Barrier Protects Against Neural Stem Cell Aging

Researchers have identified how neural stem cells remain relatively free of age related damage.

Featured Genetics

·May 20, 2016·4 min read

Enzyme Pair Play Crucial Role in Maintaining Balance of Cellular Processes

Findings could help researchers better understand how certain neurodegenerative diseases may arise.

Featured Neuroscience Open Neuroscience Articles

·May 29, 2016·4 min read

Guarding the Gatekeepers: New Player in Calcium Signalling Pathways Discovered

Researchers have identified a protein, called septin 7, that functions as a molecular break to Orai activation.

Featured Neuroscience Open Neuroscience Articles

·April 28, 2016·4 min read

How Myosin-Va Helps Direct Neuron Growth

Researchers have identified a protein that helps direct axon growth.

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