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Cold Spring Harbor Laboratory

Featured Genetics Neuroscience Open Neuroscience Articles

·March 13, 2019·4 min read

New Cell Subtypes Classified in Mouse Brain

A new process for classifying neurons in the brains of mice has been outlined by researchers from Cold Spring Harbor Laboratory. The platform pairs microscopy with genetic labeling at single neuron resolution, allowing researchers to reconstruct the brain, by providing information on every neuronal type's location.

Featured Neurology Open Neuroscience Articles

·January 20, 2019·3 min read

Targeting ‘Hidden Pocket’ For Treatment of Stroke and Seizure

Study reveals a motif on the 93-series compound fits into a tiny pocket within the NMDA receptor. The findings could lead to new treatment options for stroke and seizures, researchers report.

Featured Neuroscience

·June 6, 2018·4 min read

A Better Way to Trace Neural Pathways

Researchers have improved retrograde virus tracing to better reconstruct neural circuits in rats and mice.

Featured Neuroscience

·May 29, 2018·3 min read

How a Brain Circuit Generates Anxiety

Researchers have identified a specific circuit in the brain's central amygdala that raises anxiety levels. The study could pave the way for the development of new treatments for anxiety disorders.

Featured Neuroscience

·November 3, 2017·4 min read

How Newborn Neurons Find Their Proper Place in the Adult Brain

CSHL researchers document how neuroblasts make their journey through the rostral migratory stream to their target destination in the olfactory bulb.

Featured Neuroscience

·October 23, 2017·4 min read

Researchers Revise Our Knowledge of How the Brain Learns to Fear

Researchers report conventional understanding of fear learning may be incorrect. Contrary to popular thought, the central amygdala, and not the lateral amygdala may be the seat of aversive learning.

Featured Neuroscience Open Neuroscience Articles

·October 5, 2017·5 min read

Mouse Cell Type Census Reveals Gender Specific Brain Differences

A multiyear study reveals, contrary to expectations, numbers and ratios of three major inhibitory cell types vary stereo-typically across different cortical parts. Additionally, researchers identified 11 subcortical areas with gender specific differences in mice.

This image shows the 6 known inhibitory cell types.

Featured Genetics Neuroscience

·September 21, 2017·4 min read

Neuron Types in Brain Are Defined by Gene Activity Shaping Their Communication Patterns

A new Cell study reports on the molecular-genetic basis of neural cell types. The study reports families of gene encoding proteins involved in neurotransmission define neurons by determining which cells they connect to and how they communicate.