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circadian rhythm

Featured Neuroscience Visual Neuroscience

·April 30, 2020·2 min read

Eyes send an unexpected signal to the brain

A new study puts into question conventional belief that the eyes communicate with the brain exclusively via one signaling pathway. Researchers have identified a subset of retinal neurons that sends inhibitory signals to the brain. This subset of neurons is also involved in the synchronization of circadian rhythms to light/dark cycles and pupil constriction to bright light intensity.

Featured Genetics Neuroscience

·April 1, 2020·2 min read

The discovery of new compounds for acting on the circadian clock

Two small molecules, KL101 and TH301, are the first compounds that selectively target circadian clock components CRY1 and CRY2.

This shows children putting their hands together

Featured Neuroscience Neuroscience Videos Psychology

·March 11, 2020·4 min read

Older children’s brains respond differently to rewarding vs. negative experiences late in day

Older children have stronger neural responses to rewards over punishments later in the afternoon. In younger children, this pattern is reversed.

Featured Neuroscience

·March 2, 2020·4 min read

Irregular sleep may increase risk of cardiovascular events

Inconsistent bedtimes and irregular sleep patterns could more than double the risk of developing cardiovascular disease.

Featured Neuroscience Open Neuroscience Articles

·February 29, 2020·3 min read

When should you eat to manage your weight? Breakfast, not late-night snacks

Losing weight isn't just a case of restricting the foods or calories you eat, it also comes down to when you eat. Skipping breakfast and snacking late at night delays the body's fat-burning mechanisms.

Featured Genetics Neuroscience

·February 19, 2020·4 min read

Bmal1 gene is not an essential regulator of circadian rhythms

Deleting the circadian rhythm-associated BMAL1 gene in animal models, researchers discovered tissue continued to follow a 24-hour rhythm, even in the absence of external stimuli that can influence the cycle.

Featured Neuroscience Open Neuroscience Articles

·February 18, 2020·3 min read

Time of day affects global brain fluctuations

The strength of the brain's global signal fluctuation decreases as the day progresses.

This shows a clock and the structure of CK1

Featured Genetics Neuroscience Open Neuroscience Articles

·February 13, 2020·5 min read

Molecular switch mechanism explains how mutations shorten biological clocks

Study reveals how certain genetic mutations can shorten the timing of the circadian clock, making some people extreme "morning larks" because their internal clock operates on a 20-hour cycle, as opposed to a 24-hour cycle.

Featured Neuroscience

·February 11, 2020·8 min read

Novel melatonin receptor molecules make possible therapies to adjust biological clock

Researchers identified molecules that can modulate circadian rhythms by binding to the MT1 melatonin receptor in the hypothalamus.

This shows two clocks set one hour apart

Brain Cancer Featured Neurology Neuroscience

·January 21, 2020·2 min read

Chronobiologists warn of health risks linked to daylight saving

Chronobiologists warn changing to daylight savings can have serious effects on both brain and general health. The change in time during spring was linked to a 24% increase in severe cardiovascular events in women. Researchers also noted the sudden change in time alters circadian rhythms, reduces the production of natural melatonin, impacts cognitive function, and may also foster tumor growth.