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          cAMP

          Image shows a diseased neuron in Alzheimer's dementia.
          FeaturedNeurologyOpen Neuroscience Articles
          ·March 7, 2017·4 min read

          Caffeine Boosts Enzyme That Could Protect Against Dementia

          Researchers have discovered 24 compounds, including caffeine, that have the potential to boost NMNAT2, an enzyme shown to help protect against dementia.
          Read More
          Image shows a diagram of the creb interaction with cre.
          FeaturedNeuroscience
          ·December 27, 2016·4 min read

          Novel Insights Into Neuronal Activity-Dependent Gene Expression by CREB

          A new study explores how neural activity influences CREB dynamics.
          Read More
          Image shows healthy axons.
          FeaturedNeurology
          ·August 8, 2016·5 min read

          Beneficial Role Clarified for Brain Protein Associated with Mad Cow Disease

          Researchers report a protein normally associated with prion diseases may help to maintain myelin.
          Read More
          Image shows the crystal structure of the cAMP-degrading enzyme phosphodiesterase PDE3B.
          FeaturedNeuroscience
          ·June 10, 2016·5 min read

          Copper is Essential for Burning Fat

          Researchers report that without enough copper, fat builds up in fat cells without being used.
          Read More
          Image shows proteasomes.
          FeaturedGeneticsNeurology
          ·December 21, 2015·4 min read

          Slowing Alzheimer’s by Speeding Up Brain’s Waste Disposal

          Researchers identify a therapeutic target for clearing toxic proteins in Alzheimer's and other neurodegenerative diseases.
          Read More
          Image of a zebrafish neuron.
          FeaturedNeuroscience
          ·November 17, 2015·3 min read

          Repairing Neurons With Light

          Researchers have successfully repaired an injured neural circuit in a zebrafish using optogenetics.
          Read More
          Outline of a person with pain points highlighted.
          FeaturedNeurologyPain
          ·October 12, 2015·4 min read

          Chronic Pain is in the Brain

          A new study reports on the role of HCN channels in pain processing.
          Read More
          Illustration of olfactory sensory neurons in a mouse nose.
          FeaturedNeuroscience
          ·September 10, 2015·5 min read

          Cilia Length Affects Sensitivity to Odors

          Location and length of cilia in nasal cavity impacts sensitivity to smell, a new study reports.
          Read More
          This image shows an outline of a head with a DNA double helix in it.
          FeaturedGenetics
          ·August 14, 2015·4 min read

          New Hope of Better Treatments For Alzheimer’s Disease Thanks to ‘Brainy’ Mice

          A new study reports that in behavioral tests, PDE4B inhibited mice showed enhanced cognitive abilities. The findings could help researchers develop new treatments for cognitive disorders.
          Read More
          This image shows the anatomy to the VTA with the striatum, nucleus accumbens and substantia nigra labelled.
          FeaturedPsychology
          ·July 21, 2015·3 min read

          A New Target For Depression Treatment

          Researchers have identified a potential new target to treat recurring depression.
          Read More
          This image shows the molecular structure of cAMP.
          FeaturedNeuroscience
          ·January 20, 2015·2 min read

          A Chemical Modified Version of the Second Messenger cAMP

          A new paper describes the development of a cAMP analogue which specifically activates only Epac2.
          Read More
          This image shows a mouse hippocampus stained green.
          ElectrophysiologyFeaturedNeuroscience
          ·November 18, 2014·4 min read

          Researchers Prevent Memory Problems Caused by Sleep Deprivation

          Researchers report a particular set of cells in the hippocampus are responsible for memory problems following sleep deprivation.
          Read More
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          A 3D digital illustration of a human brain side-by-side comparison, highlighting the language centers glowing brightly and equally in both a younger and older brain, while executive function areas are dimmed in the older brain.

          Aging Brains Maintain Robust Language Networks Despite Cognitive Decline

          Rejuvenation of Microglia by Youth Protein TIMP2 in the Aging Brain

          Youth Protein TIMP2 Restores Immune Function in the Aging Brain

          A multi-panel documentary photo. Left: A Black man sits alone on a locker room bench with his head down. Center: A Latino man sits withdrawn at a family kitchen table. Right: A White man looks thoughtfully at wellness pamphlets in a public waiting area. All convey isolation.

          Shame, Stigma, and Culture Prevent Male Domestic Violence Survivors From Seeking Help

          Alternative graphical abstract is shown.

          Study of Brain Immune Cells Reveals New Clues to Alzheimer’s Disease Progression

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