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cAMP

Featured Neuroscience

·January 20, 2015·2 min read

A Chemical Modified Version of the Second Messenger cAMP

A new paper describes the development of a cAMP analogue which specifically activates only Epac2.

This shows two people with loud speakers as head

Auditory Neuroscience Electrophysiology Featured Neuroscience

·July 22, 2022·3 min read

A New Mechanism Responsible for Controlling Auditory Sensitivity

Researchers identified a new mechanism by which auditory sensitivity is regulated. The mechanism can temporarily reduce sensitivity in the auditory system to protect itself from loud sounds that can cause hearing damage.

This image shows the anatomy to the VTA with the striatum, nucleus accumbens and substantia nigra labelled.

Featured Psychology

·July 21, 2015·3 min read

A New Target For Depression Treatment

Researchers have identified a potential new target to treat recurring depression.

Image shows the researcher testing beer.

Featured Neuroscience Open Neuroscience Articles Psychology

·September 30, 2017·4 min read

Beer Can Lift Your Spirits: Hordenine Activates Brain’s Reward Center

Hordenine, a substance present in beer and malted barley, activates dopamine D2 receptors through G proteins, leading to a possibly prolonged effect on the brain's reward center, researchers report.

Featured Neurology

·August 8, 2016·5 min read

Beneficial Role Clarified for Brain Protein Associated with Mad Cow Disease

Researchers report a protein normally associated with prion diseases may help to maintain myelin.

Featured Neurology

·August 20, 2012·2 min read

Brain Enzyme is Double Whammy for Alzheimer’s Disease

Researchers discover that an enzyme known for generating toxic brain plaques in Alzheimer's disease also causes additional memory and cognitive deficits via a separate mechanism. They found that BACE1 disrupts the cell's production of other molecules required for PKA function. By that mechanism, BACE1 inactivates PKA and therefore inhibits memory formation in mice, even in the absence of neurotoxic β-amyloid.

Image shows a diseased neuron in Alzheimer's dementia.

Featured Neurology Open Neuroscience Articles

·March 7, 2017·4 min read

Caffeine Boosts Enzyme That Could Protect Against Dementia

Researchers have discovered 24 compounds, including caffeine, that have the potential to boost NMNAT2, an enzyme shown to help protect against dementia.

Image shows a chemical diagram of caffeine.

Featured Neurology

·August 1, 2017·3 min read

Caffeine Shortens Recovery Time From General Anesthesia

A new study reveals animals injected with caffeine during the last 10 minutes of exposure to general anesthetic woke more quickly than those injected with saline solution. Waking times became significantly quicker with higher doses of caffeine.