Removing body clock gene protects mice against pneumonia
Removing BMAL1, a gene commonly associated with circadian rhythm, makes macrophages more effective and the body more resistant to pneumonia.... Read More...
BMAL1
Body parts respond to day and night independently from brain
Skin and liver cells appear to have their own circadian clock. Both the liver and skin respond to changes in light and maintain critical function, independent of the brain's circadian rhythm.... Read More...
Gene-edited disease monkeys cloned in China
Researchers in China successfully used CRISPR gene editing to produce five monkey clones from the fibroblasts of a donor monkey with disease phenotypes. ... Read More...
How Fasting Can Improve Overall Health
Researchers report fasting affects the circadian rhythm of the liver and skeletal muscles, allowing them to rewire their metabolism. The study suggests fasting can help improve health and protect against aging related diseases.... Read More...
How the Body Clock Controls Inflammation
A new study sheds light on how the circadian clock controls inflammatory response. By understanding the link between inflammation and circadian rhythm, researchers believe it may be most effective to target specific conditions at certain times of the day. The findings may also explain why those who experience body clock disruptions are more susceptible to inflammatory conditions.... Read More...
Cancer Overrides the Circadian Clock to Survive
A new study reports misfolded proteins can cause circadian rhythm disruptions which contribute to cancerous tumor growth.... Read More...
Time of Day Affects Severity of Autoimmune Disease
Researchers shed light on how the circadian rhythm and time of day impact immune response in autoimmune diseases. The findings could help in the development of new treatments to tackle a range of autoimmune disorders.... Read More...
Sleep Biology Discovery Could Lead to New Insomnia Treatments That Don’t Target the Brain
According to researchers, increasing levels of Bmal1 in the skeletal muscles of mice makes the animals resistant to insomnia and sleep deprivation. The findings could provide a new treatment target for sleep disorders.... Read More...
Muscle, Not Brain, May Hold Answers to Some Sleep Disorders
A new study reveals mice with higher levels of BMAL1 in their muscles were able to recover from sleep deprivation more quickly than those with the protein removed.... Read More...
Depressive Behaviors Caused by Disrupting Brain’s Internal Clock: Mouse Study
A new study reports that disrupting the natural circadian rhythm in mice causes depression and anxiety.... Read More...
Time of Day Influences Susceptibility to Infection
A new study reveals we are more susceptible to infections at certain times of the day as our circadian rhythm affects the ability of the virus to spread and replicate.... Read More...
Why Working the Night Shift Can Pose a Cancer Risk
A new study reports on a link between circadian cell disruption and cancerous tumor growth.... Read More...