Skin cells may hold the key to explaining why women are more prone to developing autoimmune diseases, such as lupus than men. Researchers found women have more VGLL3 in their skin cells than men. VGLL3 pushes the immune system into overdrive, resulting in the 'self-attacking' autoimmune response, the mouse study revealed. Findings strongly implicate VGLL3 as a pivotal catalyst in sex-based autoimmunity.
A study in mouse models of multiple sclerosis demonstrates a compound called sobetirome promotes remyelination, and a derivative of the compound can penetrate the blood-brain barrier to enable a tenfold increase in infiltration to the CNS. Researchers are confident their research will translate from mice into humans, providing a new avenue of treatment for MS.
Non-invasive vagus nerve stimulation reduces inflammation and improves symptoms for those suffering from rheumatoid arthritis. The simulation technique helps inhibit the production of cytokines and reduces inflammatory response.
Vitamin D causes dendritic cells to produce more CD31, hindering the activation of T cells. The study sheds light on how vitamin D deficiency regulates the immune system and can lead to autoimmune diseases, like multiple sclerosis.
18% of new patients treated at two Los Angeles hospitals for multiple sclerosis were misdiagnosed with the autoimmune disease. The misdiagnosed patients were often treated unnecessarily with medications designed for MS. From their findings, researchers report the most common alternative diagnosis was migraine.
Study finds no association between mineral levels or dietary mineral intake and an increased risk of multiple sclerosis.
A new biomarker for fibromyalgia has been identified in blood samples taken from patients suffering from the condition.
A new study reports intensive therapy during the early stages of MS results in better long term outcomes for the patients.
A new study reveals a link between food allergies and relapses in Multiple Sclerosis.
Researchers report those who experience chronic inflammation during middle may be at increased risk of developing cognitive and memory disorders during old age.
Studying animal models, researchers have identified previously unknown types of immune cells that are present in the brains of those with multiple sclerosis.