Researchers link the Human Herpes Virus 6A to the development of multiple sclerosis.
Chronic social stress in mice induces the expression of virulent genes in the gut microbiota. The altered microbiota increases the presence of effector T helper cells in the lymph nodes and induces myelin autoreactive cells. Exposure to chronic stress, therefore, may increase the risk of developing autoimmune diseases for some individuals with a susceptibility.
TH17 cells produced increased amounts of SerpinB1, a protein implicated in multiple sclerosis symptoms. SerpinB1 cells were identified with antibodies targeting the CXCR6 surface protein. Using monoclonal antibodies to target CXCR6, the cells disappeared significantly, and the mice primed to develop MS did not develop the disease.
A new study reports low impact exercise, such as yoga and swimming, can help improve certain symptoms of multiple sclerosis.
Vitamin D causes dendritic cells to produce more CD31, hindering the activation of T cells. The study sheds light on how vitamin D deficiency regulates the immune system and can lead to autoimmune diseases, like multiple sclerosis.
Study reveals mice with antibody-induced rheumatoid arthritis went on to develop spinal lesions similar to those associated with axial spondyloarthritis.
Clotting proteins are elevated in the urine of patients with lupus nephritis. The findings provide a new biomarker for the autoimmune disease.
A new study reports the loss of the Bim protein in macrophages leads to lupus-like symptoms in mice. The findings may help in the development of new treatments for the autoimmune disease in humans.
Researchers have discovered a possible trigger for autoimmune diseases such as lupus, Crohn's disease and MS. Findings may explain how women are more susceptible to autoimmune disorders than men.
Common antiretroviral therapies used to treat HIV/AIDS can disrupt the function of oligodendrocytes which are critical for the manufacturing of myelin, a new study reports.
T cells that react to alpha-synuclein are most abundant in the early stages of Parkinson's disease but tend to disappear as the disease progresses. Signs of autoimmunity can appear in Parkinson's patients up to ten years before a diagnosis of the neurodegenerative disease. The detection of T cell response could be an early biomarker for Parkinson's, long before the physical symptoms begin to manifest.
Researchers discover a way in which to prevent immune attacks on viruses used as therapeutic treatments.
