autoimmune diseases

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autoimmune diseases

·July 10, 2019·3 min read

Brain on Fire: Puzzling brain disease could now be better diagnosed and treated

A rare autoimmune disorder popularized by the autobiography and movie "Brain on Fire" is triggered by an attack on NMDA receptors. The disease occurs when antibodies attack NMDA receptors in the brain, leading to memory loss, intellectual changes, seizures, and death. Read More

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·July 2, 2019·3 min read

B cells off the rails early in lupus

A key finding in the origins of lupus has been discovered. In those with systemic lupus erythematosus, B cells are abnormally activated. This results in the production of antibodies which react against the patient's own tissue, causing a range of symptoms including rashes, joint pain, and fatigue. Read More

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·June 29, 2019·4 min read

Newly discovered immune cells at the frontline of HIV infection

A newly discovered subset of dendritic cells have been implicated in sexually transmitted HIV infection. The CD11c+ dendritic cells are found in human genital tissue at the epithelial level. They are the first immune cells to interact with the HIV virus. The cells directly transfer the virus to CD4 T cells, making them key drivers in HIV transmission. Read More

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·June 20, 2019·5 min read

Fibromyalgia linked to variations in microbiome composition

Using a range of clinical techniques, including deep learning, researcher identify changes in the microbiome of people with fibromyalgia which were not associated with diet, medications or aging. Additionally, the severity of symptoms was directly correlated with an increased presence, or more pronounced absence, of certain bacterias. Read More

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Featured Neurology Neuroscience

·June 12, 2019·4 min read

Women caught in a pickle by their own immune systems

Pregnancy Compensation Hypothesis may explain why women are more prone to developing autoimmune diseases, like multiple sclerosis and lupus, than men. Read More

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·June 6, 2019·3 min read

12 genes at the root of multiple sclerosis identified

12 genes associated with familial multiple sclerosis have been identified. The findings provide a molecular rationale for the chronic inflammation, demyelination and neurodegeneration associated with MS. Identifying new genetic targets could help with the development of novel treatments to prevent multiple sclerosis in those with a genetic risk. Read More

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·June 5, 2019·3 min read

Nanotechnology treatment reverses multiple sclerosis in mice

Extracting nanosized exosomes from bone marrow stem cells and injecting them into mice, researchers reverse symptoms of multiple sclerosis. Read More

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·May 29, 2019·4 min read

New compounds could be used to treat autoimmune disorders

Researchers have developed small molecules that inhibit one of the main enzymes implicated in autoimmune response. The research could lead to potential new medications for a range of autoimmune diseases. Read More

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·May 26, 2019·6 min read

Autoimmune disease and stress: Is there a link?

Researchers consider why those with autoimmune diseases are more likely to have a previous diagnosis of stress-related disorders. Read More

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·May 17, 2019·3 min read

Groundbreaking genetic discovery shows why Lupus develops

Rare gene variants BLK and BANK1 are present in a substantial percentage of people with Lupus. The genetic variants suppress 1RF5 and type-1 1Fn in B cells, causing dysfunction in the immune cells. Read More

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·May 14, 2019·4 min read

How stressed-out gut bacteria may trigger autoimmune response

Chronic social stress in mice induces the expression of virulent genes in the gut microbiota. The altered microbiota increases the presence of effector T helper cells in the lymph nodes and induces myelin autoreactive cells. Exposure to chronic stress, therefore, may increase the risk of developing autoimmune diseases for some individuals with a susceptibility. Read More

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·April 23, 2019·3 min read

Microglia, immune cells of the central nervous system, shown to regulate neuroinflammation

In uveitis, microglia facilitates the entry of inflammatory immune cells into the retina, enabling the host immune responses to attack cells not normally recognized by the immune system. Read More

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