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autoimmune diseases

·May 2, 2024·7 min read

Myelin Repair Provides Novel Multiple Sclerosis Treatment

Researchers discovered a promising treatment for multiple sclerosis (MS) using a novel protein function inhibitor, ESI1, which effectively regenerates myelin—a crucial protective coating on nerve cells that deteriorates in MS. The study showcases that ESI1 reactivates the brain's capacity to produce myelin, overcoming traditional barriers that have hindered myelin regeneration.

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·April 19, 2024·7 min read

Blood Test Predicts Multiple Sclerosis Years Before Symptoms Appear

Researchers identified a specific pattern of autoantibodies in the blood that precedes the clinical onset of multiple sclerosis (MS), potentially paving the way for early diagnosis and treatment. Their study found that 10% of MS patients displayed a unique set of autoantibodies against both human proteins and common pathogens like the Epstein-Barr Virus years before showing symptoms.

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·June 12, 2023·8 min read

Cellular Custodians: ‘Big Eater’ Macrophages May Hold Key to Autoimmune Disease Treatment

The mysterious workings of tingible body macrophages (TBMs) have been substantially demystified. These TBMs, a subtype of macrophages within our lymph nodes, were found to devour antibody-producing B cells, a function essential in defending our bodies against harmful pathogens.

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·February 15, 2023·4 min read

Multiple Sclerosis Discovery Could End Disease’s Chronic Inflammation

Blocking the activity of the reactor called the aryl hydrocarbon receptor in T cells resulted in both a decrease in inflammation and recovery in mouse models of multiple sclerosis.

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·February 9, 2023·5 min read

New Biomarker for Disease Progression in Multiple Sclerosis

The blood level of the glial fibrillary acidic protein (GFAP) cellular component increases when astrocytes are damaged or activated. Elevated levels of GFAP in the blood can indicate both the current and future progression of multiple sclerosis.

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·January 5, 2023·5 min read

Intestinal Bacteria May Be an Important Piece in the Jigsaw Puzzle of Multiple Sclerosis

Study reveals differences in the composition and functionality of intestinal bacteria of multiple sclerosis patients depending on whether their illness is active or whether they are in treatment.

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·December 10, 2022·6 min read

Harnessing the Brain’s Immune Cells to Stave off Alzheimer’s and Other Neurodegenerative Diseases

Researchers have identified a protein that could be leveraged to help microglia in the brain stave off Alzheimer's and other neurodegenerative diseases.

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·December 7, 2022·2 min read

New Genes Linked to Multiple Sclerosis Discovered

Study identified three new genes that appear to be involved in the pathologies associated with multiple sclerosis.

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·December 6, 2022·5 min read

Immunotherapy Eliminates Disease-Causing Cells in Multiple Sclerosis-Like Disease

CAR-T, a therapy generally used in the treatment of cancer, has been shown to eliminate unhealthy cells that trigger autoimmunity in mouse models of multiple-sclerosis.

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·November 10, 2022·5 min read

Blood Stem Cell Transplant Could Reboot Immune System in Multiple Sclerosis Patients

80% of patients with multiple sclerosis remain disease-free for the long term following an autologous hematopoietic stem cell transplant.

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·November 7, 2022·5 min read

Changing Treatment Can Help Multiple Sclerosis Patients

The number of relapses in patients with relapsing-remitting multiple sclerosis was better controlled and symptoms of disability were stabilized or improved when patients who discontinued fingolimod changed to either ocrelizumab or natalizumab.

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·September 27, 2022·4 min read

Diet High in Guar Gum Fiber Limits Inflammation and Multiple Sclerosis Symptoms

Diets high in guar gum, a dietary fiber and common food additive extracted from guar beans, limit inflammation and delay the onset of multiple sclerosis in mouse models.