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AUD

·March 29, 2024·5 min read

Compound May Curb Alcohol Dependence

The compound LY2444296, which blocks the kappa opioid receptor, significantly reduces alcohol consumption in animal models of alcohol dependence. This study suggests LY2444296 could be a breakthrough in treating alcohol use disorder (AUD) by targeting the brain's KOP system, implicated in addiction and withdrawal symptoms.

Featured Genetics Neurology Neuroscience

·March 27, 2024·4 min read

Diabetes, Pollution, and Alcohol Amplify Dementia Risk

Researchers identified key risk factors and genetic influences impacting a specific brain network vulnerable to aging, schizophrenia, and Alzheimer’s disease. This 'weak spot' in the brain is especially susceptible to diabetes, air pollution, and alcohol consumption.

Featured Neuroscience Psychology

·March 21, 2024·6 min read

Targeting Stress Neurons Could Curb Problem Alcohol Use

Researchers made a significant discovery, identifying that inhibiting neurons related to stress responses may decrease alcohol consumption in individuals suffering from post-traumatic stress disorder (PTSD) and alcohol use disorder (AUD) simultaneously. Their study used a rat model to demonstrate that reducing the activity of corticotropin-releasing factor (CRF) producing neurons in the central amygdala lessens alcohol intake without affecting trauma-related anxiety.

Featured Genetics Neuroscience

·December 26, 2023·4 min read

Global Genetic Insights into Problematic Alcohol Use

A new study uncovers a shared genetic basis for problematic alcohol use (PAU) across diverse ancestries. This research broadens our understanding of PAU's genetic architecture and its consequences, including its role as a major cause of health problems and death.

This shows a man and empty drinking glasses.

Featured Genetics Neuroscience Psychology

·December 1, 2023·4 min read

Peptide PACAP’s Key Role in Alcohol Addiction

Alcohol, the world's most common addictive substance, leads to $249 billion in annual costs and 88,000 deaths in the U.S. Alcohol use disorder affects millions but is under-treated. Researchers discovered a key player in alcohol addiction: pituitary adenylate cyclase activating polypeptide (PACAP).

This shows a teenage girl surrounded by leaves.

Featured Neuroscience Psychology

·November 30, 2023·9 min read

Cannabis and Alcohol Co-use Impacts Adolescent Brain and Behavior

Recent studies reveal effects of cannabis and alcohol co-use on adolescent rats, simulating human behavior. Rats voluntarily consumed THC-infused treats and alcohol, allowing researchers to observe changes in brain structure and behavior.

Featured Neurology Neuroscience

·October 31, 2023·4 min read

Hormonal Link in Alcohol Withdrawal Headaches

Alcohol use disorder impacts 283 million individuals globally, with limited therapeutic options. Researchers discovered a significant connection between the stress hormone, corticotropin-releasing factor (CRF), and alcohol-withdrawal headaches.

This shows a woman with glasses of wine and a plate of food.

Featured Genetics Neuroscience Psychology

·September 18, 2023·5 min read

Genetic Link Between Eating Disorders and Alcohol Use Discovered

A comprehensive study of adolescent twins unveils a genetic nexus between disordered eating and alcohol use disorders (AUDs). This correlation underscores worse outcomes, including fatality, especially when these conditions manifest simultaneously in younger teens.

Featured Genetics Neuroscience

·July 17, 2023·5 min read

Neuronal Plasticity Genes Linked to Alcohol Use Disorders

A new study discovered a link between alcohol use disorders (AUDs) and alteration of a group of genes known to influence neuronal plasticity and pain perceptions. The team used three distinct animal models to identify the genes responsible for drinking behaviors.

Featured Neuroscience Psychology

·June 19, 2023·8 min read

Alcohol Use Disorder: More Alcohol, More Impairment, Regardless of Drinking Habits

Researchers reveal the idea of "holding one's liquor" is complex, particularly among heavy drinkers. The study shows that while individuals with alcohol use disorder (AUD) display less impairment after consuming a standard intoxicating dose, they exhibit significantly more impairment when the consumption aligns with their usual heavier drinking habits.

Featured Neuroscience Psychology

·June 15, 2023·3 min read

Heavy Drinkers Misjudge Impairment Levels: A Risky Perception

Heavy drinkers' belief that they can 'hold their liquor' better than light drinkers has been challenged by a new study, revealing that this perceived tolerance may lead to risky decisions. The research showed that after consuming equivalent amounts of alcohol, heavy drinkers felt less impaired than their lighter-drinking counterparts.

Featured Neurology Neuroscience

·June 12, 2023·6 min read

Alcohol in Excess Hastens Alzheimer’s Progression

Repeated alcohol intoxication can speed up Alzheimer’s disease progression associated with a genetic predisposition. The research demonstrated that mice exposed to consistent alcohol intoxication showed cognitive decline about two months earlier than typically expected.

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AUD

Compound May Curb Alcohol Dependence

Diabetes, Pollution, and Alcohol Amplify Dementia Risk

Targeting Stress Neurons Could Curb Problem Alcohol Use

Global Genetic Insights into Problematic Alcohol Use

Peptide PACAP’s Key Role in Alcohol Addiction

Cannabis and Alcohol Co-use Impacts Adolescent Brain and Behavior

Hormonal Link in Alcohol Withdrawal Headaches

Genetic Link Between Eating Disorders and Alcohol Use Discovered

Neuronal Plasticity Genes Linked to Alcohol Use Disorders

Alcohol Use Disorder: More Alcohol, More Impairment, Regardless of Drinking Habits

Heavy Drinkers Misjudge Impairment Levels: A Risky Perception

Alcohol in Excess Hastens Alzheimer’s Progression

How the Brain Maps Every Number

Non-Drug Breakthrough for Postpartum Depression

Cancer Drug Halts Fragile Brain Bleeds

Astrocyte Subtypes Drive Synapse Formation and Memory

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