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AUD

·June 19, 2023·8 min read

Alcohol Use Disorder: More Alcohol, More Impairment, Regardless of Drinking Habits

Researchers reveal the idea of "holding one's liquor" is complex, particularly among heavy drinkers. The study shows that while individuals with alcohol use disorder (AUD) display less impairment after consuming a standard intoxicating dose, they exhibit significantly more impairment when the consumption aligns with their usual heavier drinking habits.

Featured Neurology Neuroscience Open Neuroscience Articles

·September 9, 2020·4 min read

Vitamin B1 Deficiency a Key Factor in the Development of Alcohol-Related Dementia

Researchers hypothesize vitamin B1 (thiamine) deficiency may play a significant role in dementia associated with alcohol use disorder. It is known iron deposits in the brain contribute to neurodegenerative diseases. Those with AUD have elevated levels of both iron in their blood and thiamine deficiency. Thiamine is vital for maintaining the blood-brain barrier. Thiamine deficiency associated with AUD disrupts the integrity of the BBB, allowing for more iron deposits within the brain and leading to oxidative tissue damage.

Featured Genetics Neurology Neuroscience

·August 8, 2024·5 min read

Parental Alcohol Use Linked to Early Aging in Kids

Children of parents with alcohol use disorders inherit early aging symptoms, including high cholesterol, heart problems, arthritis, and early-onset dementia. This effect is worse if both parents have alcohol issues, especially in male offspring, due to mitochondrial dysfunction inherited from parents. Researchers suggest that improving mitochondrial health through exercise and vitamin intake could help delay these effects.

Featured Neuroscience Psychology

·July 11, 2022·3 min read

Drinking Alone Foreshadows Future Alcohol Problems

Adolescents and young adults who drink alone are at greater risk of developing alcohol use disorder later in life.

This shows a person holding a glass of scotch and microglia.

Featured Neuroscience Psychology

·October 13, 2026·5 min read

Alcohol Tricks Brain Cells Into Destroying Themselves

Researchers discover microglia tear down brain scaffolding during heavy drinking, driving alcohol sedation and frontal brain damage.

Featured Genetics Neuroscience

·May 6, 2025·6 min read

Romantic Partners Can Shape Genetic Risk for Binge Drinking

New research shows that romantic partners' habits and traits can influence how strongly genetic risk for binge drinking affects an individual. Using data from Finnish twins, scientists found that partners who smoke, show psychological distress, or exhibit low conscientiousness amplify genetic risk.

Featured Neurology Neuroscience

·July 8, 2026·11 min read

Alcohol Alters Brain Flexibility Based on Hidden Dementia Markings

Alcohol interacts differently with amyloid-beta and tau pathologies in the brain's corticostriatal circuit.

Featured Neuroscience Psychology

·February 7, 2023·5 min read

Differences in Dopamine Signals in Patients With History of Alcohol Use Disorder

The connection between dopamine and counterfactual information, or notions of relief and regret, is altered in those with alcohol use disorder.

Featured Neurology Neuroscience

·December 5, 2022·5 min read

Understanding the Risk of Dementia and Alcohol Consumption

Researchers report abstaining from drinking alcohol can actually increase dementia risks. Low to moderate alcohol consumption may help to reduce dementia risks.

Featured Neuroscience Psychology

·August 23, 2024·4 min read

Memory Cues May Help Reduce Alcohol Consumption

A study suggests that recalling past alcohol experiences before drinking can slow down consumption, indicating a potential strategy to reduce alcohol intake. In the study, women who remembered a previous drinking episode took longer to consume an alcoholic beverage, possibly due to reduced motivation to drink. This approach, along with strong health warnings, may offer new methods to curb excessive alcohol consumption. Further research is needed to explore this effect in males.

Featured Genetics Neuroscience Psychology

·July 18, 2019·4 min read

Romantic partnerships mitigate influence of genetic predisposition to alcohol consumption

For those with a genetic predisposition for alcohol use disorder (AUD), being in a romantic relationship appears to reduce the high risk to succumbing to alcohol abuse. This protective effect is limited to males only, suggesting males with a genetic risk for AUD may benefit more from romantic relationships.

Featured Genetics Neuroscience Open Neuroscience Articles

·July 19, 2022·6 min read

A Genetic Architecture Underlying Alcohol and Cigarette Abuse

Genes associated with alcohol and smoking addiction are over-represented in specific neurons, a new study reports. Researchers found genes associated with smoking were also linked to pain perception and food response while genes linked to alcohol addiction were associated with stress and learning.