Men with alcohol use disorder have diminished brain activity in areas associated with emotional processing, memory and social processing, compared to women with AUD. The findings may lead to gender-specific treatments to help relieve addition to alcohol.
Administering oxytocin blocks the enhanced motivation for drinking alcohol that fuels alcohol use disorder by blocking GABA signaling in the central nucleus of the amygdala.
Contrary to popular belief that brain changes begin to normalize immediately after ceasing alcohol consumption, a new study reveals damage to the brain continues during the first weeks of abstinence.
18 genetic variants have been identified which appear to be associated with alcohol use disorder and heavy drinking. Of these genes, five were overlapped, eight were associated with heavy consumption and five were linked to an increased risk of AUD. The study concluded that while heavy drinking is a risk factor for alcoholism, it is not a sufficient cause of the disorder.
A new study reports people who have a family history of alcohol use disorder release more dopamine in the ventral striatum as a response to the expectation of receiving an alcoholic drink than those without a family history of alcoholism.