Teenage binge drinking is linked to altered gene expression in the brain, specifically the central nucleus of the amygdala. Adolescent rats exposed to alcohol had increased levels of miR-137, resulting in lower expression of proteins essential for healthy neuron growth. During adulthood, these rats displayed higher levels of anxiety and an increased preference for alcohol consumption.
Using a novel imaging technique, researchers produce a whole mouse brain atlas, which reveals how alcohol addiction, and abstinence, alter the functional architecture of the brain.
Contrary to popular belief that brain changes begin to normalize immediately after ceasing alcohol consumption, a new study reveals damage to the brain continues during the first weeks of abstinence.
Study reveals binge drinking is associated with more widespread neural dysfunction than previously believed. In those who binge drink, the visual areas of the brain show unusually high levels of activation. Additionally, those who binge drink have more difficulty in feeling empathy for others.
Neuroimaging study reveals teens with more gray matter in the caudate nucleus and left cerebellum were at increased risk of problem alcohol use over time. The findings reinforce the idea that brain structure differences may contribute to both psychiatric and substance use disorders.
A new dual-drug therapy for alcohol use disorder appears to be effective and has fewer side effects or complications compared to other medications used to treat AUD.
Men with alcohol use disorder have diminished brain activity in areas associated with emotional processing, memory and social processing, compared to women with AUD. The findings may lead to gender-specific treatments to help relieve addition to alcohol.
Genome-wide study identifies five novel alcohol use risk loci which can pass on the risk of developing alcohol abuse disorder from parents to children.
Men who are intoxicated with alcohol have impairments when it comes to correctly assessing emotional facial cues in others. Researchers speculate the findings may explain why alcohol use is often associated with harmful interpersonal and social interactions, such as aggression and domestic violence.
Neural patterns of activity in the medial prefrontal cortex associated with the intention to drink alcohol are influenced by the genetic risk for alcohol use disorder.
People who are most sensitive to the pleasurable and rewarding effects of alcohol are at greater risk of developing alcohol use disorders.